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In medical imaging using different modalities such as MRI and CT, complementary information of a targeted organ will be captured. All the necessary information from these two modalities has to be integrated into a single image for better diagnosis and treatment of a patient. Image fusion is a process of combining useful or complementary information from multiple images into a single image. In this article, we present a new weighted average fusion algorithm to fuse MRI and CT images of a brain based on guided image filter and the image statistics. The proposed algorithm is as follows: detail layers are extracted from each source image by using guided image filter. Weights corresponding to each source image are calculated from the detail layers with help of image statistics. Then a weighted average fusion strategy is implemented to integrate source image information into a single image. Fusion performance is assessed both qualitatively and quantitatively. Proposed method is compared with the traditional and recent image fusion methods. Results showed that our algorithm yields superior performance.

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In digital photography, two or more objects of a scene cannot be focused at the same time. If we focus one object, we may lose information about other objects and vice versa. Multi-focus image fusion is a process of generating an all-in-focus image from several out-of-focus images. In this paper, we propose a new multi-focus image fusion method based on two-scale image decomposition and saliency detection using maximum symmetric surround. This method is very beneficial because the saliency map used in this method can highlight the saliency information present in the source images with well defined boundaries. A weight map construction method based on saliency information is developed in this paper. This weight map can identify the focus and defocus regions present in the image very well. So we implemented a new fusion algorithm based on weight map which integrate only focused region information into the fused image. Unlike multi-scale image fusion methods, in this method two-scale image decomposition is sufficient. So, it is computationally efficient. Proposed method is tested on several multi-focus image datasets and it is compared with traditional and recently proposed fusion methods using various fusion metrics. Results justify that our proposed method gives stable and promising performance when compared to that of the existing methods.