Background: Seasonal allergic conjunctivitis is the most common allergic disorder seen in eyes. The aim of study was to compare the clinical efficacy of combination of 0.4% ketorolac and 0.1% olopatadine with 0.4% ketorolac alone in seasonal allergic conjunctivitis. Material and Method: The study was prospective, double blind parallel group comparative. Two hundred cases enrolled in the study. All the subjects were randomly divided in two groups, 100 in each. Group 1 patients received 0.4% ketorolac eye drop in both eyes 2 times a day and group 2 patients received combination of 0.1% olopatadine and 0.4% ketorolac in both eyes 2 times a day. Observations were collected at baseline and on day 3,7,15 and analyzed statistically regarding improvement in sign and symptoms. Result: In group 1, 50-60% patients had no sign and symptoms on day 15 whereas in group 2 more than 95% patients showed improvement in clinical picture. p value was significant (p<0.0001) at day 15 in all sign and symptoms and on day 3 in itching and on day 7 in watering. Overall group 2 patients had better and earlier response regarding symptoms of itching at day 3. Conclusion: The combination of 0.1% olopatadine and 0.4% ketorolac was more effective than 0.4% ketorolac alone in seasonal allergic conjunctivitis patients.

Introduction: Acute bacterial conjunctivitis is one of the most common ocular infection seen in day to day clinical practice. Our purpose to conduct this study was to compare the outcome and efficacy of 0.6% besifloxacin ophthalmic suspension and 1.5% azithromycin ophthalmic suspension in acute bacterial conjunctivitis. Method: This is a Prospective, randomized, parallel-group, clinical study of acute bacterial conjunctivitis Conducted From July 2015 to Sept 2015 on 200 patients in the department of Ophthalmology at Jhalawar Medical College, Jhalawar.(raj.) All selected patients were divided into two groups of 100 each. Group A was treated by besifloxacin 0.6% ophthalmic suspension,where as group B was treated by 1.5% azithromycin ophthalmic suspension three times a day for 7 day. Observation was done on 3, 7 day regarding clinical resolution and side effect of these drugs in both groups. Result: Clinical resolution, complication , and side effects of these two drugs were analysed on day 3 and day 7 and found that 0.6% besifloxacin is significantly better than 1.5% azithromycin eye drop on day 3 and day 7 (p value<0.5) and also have less side effect (p value<0.5).Conclusion: 0.6% besifloxacin is safe and efficacious in acute bacterial conjunctivitis in all age group.