Introduction: Assessments of Transfusion Transmitted Diseases (TTDs) are essential for evaluating the safety of blood transfusion as well as monitoring the efficacy of current screening procedures. It also helps in formulating lifelong planning to upgrade our public health and to stop the spread of TTDs in general public.
Materials and Methods: Our objective was to find out the recent trends and seroprevalence of TTDs in voluntary blood donors at a tertiary care hospital in western part of India. A total 4117 donors are included in our study from January to December 2019. The blood samples were tested for Human Immunodeficiency Virus I and II, Hepatitis B and C virus, Syphilis and Malaria.
Results: Out of 4117 donors, a total of 39 (0.95 %) donors were positive for Transfusion Transmitted Diseases, out of which 23 (0.56%), 7(0.17%) and 9 (0.22%) donors were positive for HBV, HIV and HCV respectively.
Conclusion: The most substantial part of every blood donation is finding out accurate blood donors who are at very low risk for Transfusion Transmitted Diseases and is achieved through efficient counseling and inclusion of more sophisticated techniques for screening to reduce the transmission during the window period.
Key words : Transfusion Transmitted Diseases, blood donors, seroprevalence, Window period
Introduction: COVID-19 has impacted different age groups with increasing influence among pregnant women and their neonates. Approximately one-fifth (20%) of global annual childbirth are reported from India. So there is significant population of neonates in India which can be affected with COVID-19 infection. As most of the information about fetal outcomes and characteristics of newborn of COVID-19 infected pregnant women is available from high-income countries and less from the developing countries, so it is essential to report the same from these countries.
Methods: This longitudinal cohort study was conducted over six months from April 2021 to September 2021 in the dept. of Obstetrics and Gynaecology and Paediatrics at BPS GMC (W), Khanpur Kalan, Sonepat. All pregnant women presenting to the emergency services of the institute were tested for COVID-19. Those found positive for COVID-19 were included and followed with antenatal visits till delivery. New-born data about gestational period, gender, type of delivery, weight at birth, SARS-CoV-2 infection, management, and outcome were collected.
Results: There were 54.41% vaginal delivery, 36.77% cesarean delivery and 8.82% abortion. 14.7% of the neonates born to SARS-CoV-2 infected pregnant women, were preterm with a mean gestational age of 36.15 ± 6.81weeks, 17.74% had low birth weight with the mean birth weight of 2029.18grams and 0% had birth asphyxia while 8.47% required NICU admission. Three stillbirths (4.4%) but no neonatal death were recorded. The incidence of SARS-CoV-2 infection among neonates was 6.8%.
Conclusion: The incidence of SARS-CoV-2 infection among neonates of COVID-19 infected mothers was 6.8%. The newborns that tested positive for SARS-CoV-2 were all healthy and asymptomatic.
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