Objective Cardiovascular complications are important causes of morbidity and mortality in elective non-cardiac surgery. Although difficult to diagnose, perioperative myocardial infarction (MI) remains prognostically important. High-sensitivity troponin T (hs-TnT) assays allow detection of very minor damage to cardiac muscle. These assays are yet to be fully evaluated in the perioperative setting. Our aim was to determine the incidence and predictors of myocardial necrosis in patients at high cardiovascular risk undergoing elective non-cardiac surgery using hs-TnT.

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Objective Thyroid hormone (TH) abuse for performance enhancement in sport remains controversial and they are not prohibited in sports under the World Anti-Doping Code (WADC). However, the prevalence of TH usage in athletes is not known. Design We investigated TH use among Australian athletes undergoing anti-doping tests for competition in World Anti-Doping Agency (WADA)-compliant sports by measuring TH in serum and surveying mandatory doping control form (DCF) declarations by athletes of all drugs used in the week prior to the antidoping test. Design Serum thyroxine (T4), triiodothyronine (T3), reverse T3 (rT3) were measured by liquid chromatography-mass spectrometry (LCMS) and serum TSH, free T4 (fT4) and free T3 (fT3) by immunoassays in 498 frozen serum samples from anti-doping tests together with a separate set of 509 DCFs. Results Two athletes had biochemical thyrotoxicosis giving a prevalence of 4 per 1000 athletes (upper 95% confidence limits (CL) 16). Similarly, only two of 509 DCF’s declared usage of T4 and none for T3 also giving a prevalence of 4 (upper 95% CL 16) per 1000 athletes. These estimates were consistent with DCF analyses from international competitions and lower than the estimated T4 prescription rates in the age-matched Australian population. Conclusions There is minimal evidence for TH abuse among Australian athletes being tested for competing in WADA-compliant sports.

The attachment of a cannula connector valve to a peripheral cannula prior to blood sampling is not associated with an increase in the rate of haemolysis or hyperkalaemia.