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Optical-frequency synthesizers, which generate frequency-stable light from a single microwave-frequency reference, are revolutionizing ultrafast science and metrology, but their size, power requirement and cost need to be reduced if they are to be more widely used. Integrated-photonics microchips can be used in high-coherence applications, such as data transmission , highly optimized physical sensors and harnessing quantum states , to lower cost and increase efficiency and portability. Here we describe a method for synthesizing the absolute frequency of a lightwave signal, using integrated photonics to create a phase-coherent microwave-to-optical link. We use a heterogeneously integrated III-V/silicon tunable laser, which is guided by nonlinear frequency combs fabricated on separate silicon chips and pumped by off-chip lasers. The laser frequency output of our optical-frequency synthesizer can be programmed by a microwave clock across 4 terahertz near 1,550 nanometres (the telecommunications C-band) with 1 hertz resolution. Our measurements verify that the output of the synthesizer is exceptionally stable across this region (synthesis error of 7.7 × 10 or below). Any application of an optical-frequency source could benefit from the high-precision optical synthesis presented here. Leveraging high-volume semiconductor processing built around advanced materials could allow such low-cost, low-power and compact integrated-photonics devices to be widely used.

Optical microcavities are essential in numerous technologies and scientific disciplines. However, their application in many areas relies exclusively upon discrete microcavities in order to satisfy challenging combinations of ultra-low-loss performance (high cavity-Q-factor) and cavity design requirements. Indeed, finding a microfabrication bridge connecting ultra-high-Q device functions with micro and nanophotonic circuits has been a long-term priority of the microcavity field. Here, an integrated ridge resonator having a record Q factor over 200 million is presented. Its ultralow-loss and flexible cavity design brings performance that has been the exclusive domain of discrete silica and crytalline microcavity devices to integrated systems. Two distinctly different devices are demonstrated: soliton sources with electronic repetition rates and high-coherence Brillouin lasers. This multi-device capability and performance from a single integrated cavity platform represents a critical advance for future nanophotonic circuits and systems.Optical microcavities 1 provide diverse device functions that include frequency microcombs 2,3 , soliton modelocked microcombs 4-8 , Brillouin lasers 9-13 , bio and nanoparticle sensors 14-16 , cavity optomechanical oscillators 17 , parametric oscillators 18,19 , Raman lasers 20 , reference cavities/sources 21-24 , and quantum optical devices 25,26 . Key performance metrics improve with increasing Qfactor across all applications areas 1 . For example, higher Q factors dramatically reduce power consumption as well as phase and intensity noise in signal sources, because these quantities scale inverse quadratically with Q factor. Also, higher Q improves the ability to resolve a resonance for sensing or for frequency stabilization. Such favorable scalings of performance with Q factor have accounted for a sustained period of progress in boosting Q factor by reducing optical loss in resonators across a range of materials 27-31 . Likewise, the need for complex microcavity systems that leverage high-Q factors has driven interest in low-loss monolithically integrated resonators 28,29,[32][33][34][35][36][37][38] . For example, Q values in waveguide-integrated devices to values as high as 80 million 35 and 67 million 38 in strongly-confined resonators have been attained.Nonetheless, the highest Q-factor resonators remain discrete devices that are crystalline 39 or silica based 1,11,40,41 . These discrete resonators are moreover unique in the microcavity world in terms of overall per-formance and breadth of capability. This includes generation of electronic-repetition-rate soliton streams as required in optical clocks 42-44 and optical synthesizers 45 , rotation measurement at near-earth-rate sensitivity in micro-optical-gyros 46,47 , synthesis of high-performance microwave signals 48-51 , and operation as high-stability optical frequency references 21-23 and reference sources 24 . Functions such as these belong to a new class of compact photonic systems that rely upon ultra-high-Q fabrication m...

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Frequency combs have applications that extend from the ultra-violet into the mid-infrared bands. Microcombs, a miniature and often semiconductor-chip-based device, can potentially access most of these applications, but are currently more limited in spectral reach. Here, we demonstrate mode-locked silica microcombs with emission near the edge of the visible spectrum. By using both geometrical and mode-hybridization dispersion control, devices are engineered for soliton generation while also maintaining optical Q factors as high as 80 million. Electronics-bandwidth-compatible (20 GHz) soliton mode locking is achieved with low pumping powers (parametric oscillation threshold powers as low as 5.4 mW). These are the shortest wavelength soliton microcombs demonstrated to date and could be used in miniature optical clocks. The results should also extend to visible and potentially ultra-violet bands.

One quantitative liquid handling method in conventional assay processes is pipetting, which delivers a precise volume of one sample at a time. As this process becomes laborious and time-consuming as the number of samples increases, researchers in individual laboratories need a way to conduct large-scale assays in a reasonable amount of time and at an affordable cost. Here we report a novel handling technique of chemical substances termed 'partipetting', which allows the one-step pipetting of various chemical-laden hydrogels. We pipette and assemble various types of encoded chemical-laden microparticles in microwell arrays in parallel. The combination of this heterogeneous particle chip and a cell chip induces the release of the chemicals from the hydrogels and, eventually, the chemicals treat the targets. Based on bioassay applications using partipetting, we show its capability in large-scale bioassays, without the need for high-throughput bioassay resources, owing to a reduction in the assay costs and time.

Supercontinuum generation is demonstrated in an on-chip silica spiral waveguide by launching 180 fs pulses from an optical parametric oscillator at the center wavelength of 1330 nm. With a coupled pulse energy of 2.17 nJ, the broadest spectrum in the fundamental TM mode extends from 936 to 1888 nm (162 THz) at −50 dB from peak. There is a good agreement between the measured spectrum and a simulation using a generalized nonlinear Schrödinger equation.

Short duration, intense pulses of light can experience dramatic spectral broadening when propagating through lengths of optical fibre. This continuum generation process is caused by a combination of nonlinear optical effects including the formation of dispersive waves. Optical analogues of Cherenkov radiation, these waves allow a pulse to radiate power into a distant spectral region. In this work, efficient and coherent dispersive wave generation of visible to ultraviolet light is demonstrated in silica waveguides on a silicon chip. Unlike fibre broadeners, the arrays provide a wide range of emission wavelength choices on a single, compact chip. This new capability is used to simplify offset frequency measurements of a mode-locked frequency comb. The arrays can also enable mode-locked lasers to attain unprecedented tunable spectral reach for spectroscopy, bioimaging, tomography and metrology.