Mechanical properties and morphologies of nylon 11/ethylene‐octene copolymer blends have been investigated. The ethylene‐octene copolymer (POE) employed in this study was grafted with maleic anhydride (MAH) and thus has the potential to react with the amine group of nylon 11. Nylon 11/POE‐g‐MAH and nylon 11/POE/POE‐g‐MAH blends with varying MAH graft ratios were prepared. In this paper, the effect of MAH graft ratio on ductile‐brittle transition temperature (DBTT), mechanical properties, and morphology of blends was studied. The results showed that incorporation of POE‐g‐MAH could remarkably improve the compatibility between the nylon and POE elastomers, thus increasing the toughness of the resultant blends. The compatibilizing effect on impact strength became more pronounced with increasing MAH graft ration. DBTTs of blends were initially lowered dramatically with the increasing maleic anhydride graft ratio, but over 0.56% MAH content, DBTTs of blends did not drop further, while tensile strength and tensile modulus dropped slightly because of the decreased glass transition temperature (Tg) of nylon 11/POE blends, resulting from the increased compatibility between the two phases. The role of MAH graft ratio on the POE particle size and dispersion of POE on nylon 11 matrix was also studied.
In this study, we developed a saccharin (SAC)‐based radiopharmaceutical (
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Ga‐NOTA‐SAC) and evaluated the possibility of its application as a PET tracer in the diagnosis of carbonic anhydrase IX (CA IX)‐overexpressed tumors. We did a water‐soluble tetrazolium assay and flow cytometry analysis to identify the cell viability decrease by SAC. The radiochemical purity and stability of
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Ga‐ NOTA‐SAC in human and mouse serum was greater than 98%. The small animal PET image‐based radioactivity distribution of all organs decreased over time.
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Ga‐NOTA‐SAC presented the highest tumor‐to‐muscle ratio at 90 min post injection (p.i). The growth rates of tumor‐to‐muscle ratios of
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Ga‐NOTA‐SAC were 88% at 60 min and 220% at 90 min, compared to 30 min p.i. The potential of
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Ga‐NOTA‐SAC as a PET tracer is expected to contribute to the diagnostic research on CA IX‐overexpressed tumors with the advantages of a relatively simple synthesis method.
Supertough nylon 11 is prepared by using a plasticizer. The influence of plasticizers on the impact property and tensile properties of plasticized nylon 11 were investigated. The results show that the impact strength is improved remarkably by methylbenzene sulfonamide, and the tensile strength is almost the same as that of natural-grade nylon 11. The study of the fracture morphology on plasticized supertough nylon 11 indicates that the fracture surface of plasticized supertough nylon 11 has a special feature, which is different from the fracture surface of general ductile polymer materials. It is similar to that of a multilayer distorted lamellar structure. There are many oriented fibrillar clusters on each layer, which are perpendicular to the impact direction. This was a new breaking phenomenon, which is found on supertough nylon 11. In regard to the experimental results, a "multilayer crack extension" mechanism is put forward. The fracture of supertough nylon 6 also verified this mechanism.
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