Background: Venous thromboembolism is a leading cause of patient morbidity. In hospitalized patients with COVID-19, it is a common and potentially fatal complication. Knowledge and effective practice on VTE prophylaxis are vital for the proper management of patients. Inadequate knowledge and poor practice of health professionals towards Venous thromboembolism prophylaxis increased patients' complications. The aim of this study assess nurses' knowledge and practice regarding prevention of deep venous thrombosis among hospitalized patients with COVID-19. Design: A descriptive expletory design. Setting: The study was conducted at New Al Kasr Al Einy Teaching Hospital (Cairo University Hospitals. Egypt). Subject: A convenient sample included 100 nurses from the previously mentioned setting. Tools: Data were collected using two tools; a self-administrated questionnaire and, an observational checklist. Results: showed that, less than half of the studied nurses were more than 30 years. Majority of them were female, more than half had Institute of nursing, and majority of them had experience more than 6 years. About three quadrants of them had unsatisfactory level of knowledge and incompetent level of practice regarding prevention of deep venous thrombosis among hospitalized patients with COVID-19.
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