Donor organs shortage leads to extending criteria for deceased liver donation in the whole world.Aim:to compare results of deceased donor liver transplantation (DDLT) depending of donor age over 60 years old.Materials and methods:the study includes 390 DDLT from January 2010 to November 2017. All liver donors separated by age for two groups: I – 60 years and older (n = 26); II – younger than 60 years (n = 364). All donors were standardized by demographic, laboratory fi ndings and inotropic drug requirement. Results:no difference between both groups in severity of ischemia-reperfusion injury, ICU or in-hospital staying (median 2 and 7,5 days respectively) was found. There is also no difference between biliary or vascular complication rate. 5-year actuarial survival rate found no difference between both groups (I: 70%: II: 76%, p = 0,54).Conclusion.Using grafts from donors older than 60 years don’t worsen early and late results of DDLT. Care should be taken to avoid other risk factors (cold ischemia time, warm ischemia time).
The role of the autonomic nervous system (ANS) in chronic pain (CP) and in its chronicity is considered secondary and reactive to the nociceptive processes in the somatic nervous system (SomNS). However, research and clinical data strongly suggest the opposite. The ANS is an ancient, complex and ample part of the nervous system. It serves and controls visceral organs and somatic tissues. The ANS takes part in all aspects of all types of pain and influences its mechanisms at both peripheral and central levels. In this chapter we bring together the evidence from biomedical disciplines and clinical practice to support an alternative theory which contradicts the traditional views on the subject. We also raise questions which require further research to consolidate facts, advance our knowledge and improve treatment strategies for CP. The importance of this topic is difficult to overestimate because of the significant impact of CP on society and the lack of understanding, efficient therapy or cure.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.