OBJECTIVES: Ukraine, Japan and USA have different legislative requirements for conducting Assisted Reproductive Technologies (ART). There also exists partial government funding for ART, and growing number, type of ART cycles are observed that are conducted every year. METHODS: We analysed the type, number, and outcomes of ART cycles which started and carried out in ART clinics in Ukraine, Japan and USA in 2015 year. We calculated the rates of IVF+ICSI cycles and clinics per 1 million population in these countries. RESULTS: ART success rates vary in the context of patients, such as age, infertility diagnosis and others.In Ukraine based on the National Register of ART, there were 18,871 ART cycles performed at 33 reporting clinics, resulting in 6,450 live births. In USA based on CDC's Report, there were 231,936 ART cycles performed at 464 reporting clinics in 2015. There were 60,778 live births and 72,913 live born infants. In Japan there were 424,151 ART cycles performed at 574 reporting clinics, resulting in 510,013 live births in 2015. Japan is the only country that has been relying on guidelines only throughout the entire observation period. The government finances a state program of ART in Ukraine and in USA. The funding policy is partial in these countries. We calculated that rate of ART clinics per 1 mln population, it was 0,74 in Ukraine, 1,45 in Japan and 4,51 in USA respectively. The rate of IVF+ICSI cycles per 1 mln was 242,73 in Ukraine, 886,94 in Japan and 470,96 in USA. CONCLUSIONS: The rate of ART cycles per 1 mln population is the highest in Japan, the highest rate of ART clinics is in USA. In Ukraine the rate of cycles is 2-4 times lower than in the USA, Japan. The increasing of public funding could significantly improve the use of ART and results in Ukraine.
The Ancient Nubians have historically been renowned for their significant contributions to medicine. In spite of this, extremely poor oral health plagued this population. Paleopathological studies depict pronounced dental deterioration patterns far exceeding normal physiological progression. The advanced wear is popularly attributed to sand particle contamination of their daily diets. However, considering that individual wear mechanisms rarely act in isolation, we propose that adverse biochemical factors arising from regular consumption of tetracycline- fortified beer induced calcium malabsorption, and thus provided a synergistic diathesis in potentiating these effects. We examine these implications within the context of prevalent therapeutic remedies, bone fluorescence labeling data, and sociocultural attitudes when making the link between tetracycline and the compromised integrity of teeth, while citing the emergence of antibiotics actually predating formally-accepted convention.
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