OBJECTIVES: Ukraine, Japan and USA have different legislative requirements for conducting Assisted Reproductive Technologies (ART). There also exists partial government funding for ART, and growing number, type of ART cycles are observed that are conducted every year. METHODS: We analysed the type, number, and outcomes of ART cycles which started and carried out in ART clinics in Ukraine, Japan and USA in 2015 year. We calculated the rates of IVF+ICSI cycles and clinics per 1 million population in these countries. RESULTS: ART success rates vary in the context of patients, such as age, infertility diagnosis and others.In Ukraine based on the National Register of ART, there were 18,871 ART cycles performed at 33 reporting clinics, resulting in 6,450 live births. In USA based on CDC's Report, there were 231,936 ART cycles performed at 464 reporting clinics in 2015. There were 60,778 live births and 72,913 live born infants. In Japan there were 424,151 ART cycles performed at 574 reporting clinics, resulting in 510,013 live births in 2015. Japan is the only country that has been relying on guidelines only throughout the entire observation period. The government finances a state program of ART in Ukraine and in USA. The funding policy is partial in these countries. We calculated that rate of ART clinics per 1 mln population, it was 0,74 in Ukraine, 1,45 in Japan and 4,51 in USA respectively. The rate of IVF+ICSI cycles per 1 mln was 242,73 in Ukraine, 886,94 in Japan and 470,96 in USA. CONCLUSIONS: The rate of ART cycles per 1 mln population is the highest in Japan, the highest rate of ART clinics is in USA. In Ukraine the rate of cycles is 2-4 times lower than in the USA, Japan. The increasing of public funding could significantly improve the use of ART and results in Ukraine.
S59 self-structured questionnaire with Cronbach's alpha score of 0.829. KAP of the Subjects were assessed on a three-point Likert scale from low (1) to high (3). Post assessment, education regarding the disease, the importance of lifestyle management and treatment was provided by direct conversation and through distribution of patient information leaflets (PILs). A 3 month gap was provided after which questionnaire was readministerd to analyse the response shift of their understanding from pre to post educational program. Data collected were analyzed using descriptive statistics, t test using SPSS version 20. RESULTS: The mean age of participants was 25.54±5.18 years of which a majority belonged to 21-30 age group (76%). The pre test mean scores for KAP was 7.31±3.04, 6.26±2.19 and 6.45±2.74 (p< 0.001) while post test mean scores were 9.15±2.5, 7.42±2.33 and 7.93±2.60 (p< 0.001) respectively. Statistically significant difference was found between pre and post test (p< 0.001) regarding KAP scores of PCOS. The study revealed that there were improvements in KAP after the educational interventional program. CONCLUSIONS: Promotion of healthy lifestyles, the need for regular exercise and increased awareness programs on PCOS is the need of the hour to enable a holistic solution to this problem. The present study shows that clinical pharmacist can play a significant role in patient education and in improving patient care of such lifestyle diseases.
regarding demographic, diagnosis, prescription, proceduce and clinical outcomes were extracted. Inverse probability weights was used to account for the baseline differences in the probability to receive treatment or not. Marginal structural model were used to adjust time-varying confounding factors. Results: Our cohort included 6138 patients undergoing mechanical ventilation, 3872 (63.1%) were male, and the median age was 59 (46, 70) years. In total, 1779 (29%) VACs cases were identified, and 971 (15.8%) deaths occurred during hospitalization. There were 3479 (56.7%) patients receiving thromboembolism prophylaxis, of which, 739 (21.2) diagnosed as hypertension, and 483 (13.9) diagnosed as heart failure. Among patients receiving thromboembolism prophylaxis, 990 (28.5%) patients developed VAC, 276 (7.9%) developed IVAC, and 113(3.2) developed PVAP. Multivariable logistic regression analysis suggested that thromboprophylaxis reduced the risk of VAE (aOR 0.85, 95% CI 0.78 -0.91), IVAC (aOR 0.86, 95% CI 0.79 -0.93), and PVAP (aOR 0.89, 95% CI 0.82 -0.97). Conclusions: Thromboembolism prophylaxis may be associated with a lower risk of VAC, IVAC, and PVAP among ICU patients receiving mechanically ventilated.
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