Anti-bacterial are agents that inhibit bacterial growth or kills bacteria and are a sub-type of antimicrobials. These are drugs used to treat infections, but they sometimes pose a threat of adverse events. Some of these adverse events are neuropsychiatric, which are generally hard to diagnose and is often paid less attention. They account for about 30% of total Adverse drug reactions (ADRs) caused by drugs in patients without mental abnormalities. The spectrum ranges from episodes of seizure to acute psychosis. The article emphasizes the frequency of such adverse events and means to raise awareness among medical practitioners regarding the same. The various neuropsychiatric adverse effects and the agents responsible have been reviewed, along with their possible mechanisms and general management. The information for writing this review was selected by searching for keywords such as Neurotoxicity, GABA, Psychosis, Naranjo scale, and Antibiomania in databases such as Google Scholar, PubMed, Elsevier, etc. After searching the articles in the above-mentioned databases, the articles were screened concerning their importance with our work and according to their title and abstract. Additional articles were discovered by checking the references in the current study's citations. Using this method, the various neuropsychiatric adverse effects of Antibacterial agents were summarized in this review.
Cancer is a lethal disease that is the second leading cause of mortality in the world. According to statistics, prostate cancer is one of the most common types among men. Male hormone androgens, particularly testosterone, are required for normal growth and functioning of the prostate. In prostate cancer, activation of the androgen receptor promotes the growth of cancer cells. The goal of hormonal therapy or androgen deprivation therapy (ADT) is to reduce levels of such male hormones in the body or prevent them from stimulating cancer cells. There are many issues that have to be considered before initiation of hormonal therapy which are necessary to be aware of for its prevention and the management in routine clinical practices. In this review article, we emphasis on cardiovascular complications following ADT and certain treatment measures.
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