Background. Blackwater fever (BWF) is a rare but serious complication of malaria that is a consequence of antimalarial treatment. Its prevalence seems to have increased. Its diagnosis is based on clinical symptoms and urine color. We report on 4 BWF cases admitted to the infectious diseases department of Zinder National Hospital. Results. Four patients were hospitalized in September 2017 for a hepatorenal syndrome of jaundice, port wine-colored urine, renal failure, and hepatic cytolysis following antimalarial treatment with quinine salts. Quinine treatment was stopped and treatment was continued with injectable artemether. Three patients underwent extra-renal purification. Their evolution was favorable. One patient died less than 24 hours after admission. Conclusion. A rare and severe complication, blackwater fever must be considered for patients under antimalarial treatment who present with jaundice, abdominal pain, and acute renal insufficiency with port wine-colored urine. Rapid diagnosis and management in an intensive care unit are crucial for improving the prognosis.

Objective: To describe the epidemiological, clinical and therapeutic aspects of urethral stenosis at Zinder National Hospital (ZNH) NIGER. Patients and methods: This was a descriptive retrospective study carried out in the Department of Urology of the ZNH during the period from January 2016 to December 2019. We collected 116 medical records of patients, in whom the diagnosis of narrowed Urethral donation was performed and documented by retrograde and voiding urethro-cystography and managed. Results: During Fifteen patients (12.93) were lost to follow-up after their first evaluation. Conclusion:Stenosis of the urethra is a common condition in consultations at the NHZ. Patients often consult for complications. The UC is the key to the topographic diagnosis of the lesion. Resection with end to end anastomosis gives good results. Plasties with mucosal or skin grafting still remain a challenge in our context.