Acalypha indica L. is one of herbal plants found in wet, moderate, tropical areas which grows as a weed. This herb has been used traditionally to treat dysentery, diarrhea, malnutrition, and malaria. But chemical compounds in Acalypha indica L. hasn’t been completely reported yet. This study aims to evaluate chemical compounds and total antioxidant of Acalypha indica L. extract. The extraction of Acalypha indica L. was carried out by maceration method using methanol and ethanol as solvent. The rendemen, water and ash content of Acalypha indica L. extract determined by gravimetric methods. The DPPH method was used to determine total antioxidant and the X-Ray Fluorescence method was used to analyze of the elements contained in the extract. The yield of methanol extract was 14.83%, this was greater than the ethanol extract of Acalypha indica L. which was 5.94%. The water and ash content of the methanol extract were obtained 10.57% and 17.44% respectively, while the ethanol extract was 35.66% and 17.93%. Phytochemical screening of Acalypha indica L. in methanol and ethanol extracts showed that the extracts contained phenolic, flavonoids, steroids, terpenoids and alkaloids compounds. The total antioxidant was obtained 1.59 mg/gDW and 3.11 mg/gDW in methanol and ethanol extract. XRF analysis results showed that methanol and ethanol extract contained elements Mg, Si, Cl, K, Mn and Fe. Based on the result, it can be concluded that Acalypha indica L. extract contained some compounds and elements which is beneficial for health.
Daun Mengkudu (Morinda citrifolia L.) merupakan salah satu tumbuhan obat tradisional secara ilmiah dipercaya memiliki aktivitas antibakteri. Tujuan dari penelitian ini adalah untuk memformulasi pasta gigi dari ekstrak etanol daun mengkudu dengan variasi konsentrasi 4% (F1), 8% (F2) dan 12% (F3) serta menguji stabilitas fisiknya. Evaluasi dari sediaan pasta gigi yang dibuat meliputi uji organoleptis, uji homogenitas, uji pH, uji daya busa, uji viskositas, dan uji stabilitas. Hasil uji organoleptis dan homogenitas menunjukkan ketiga formula (F1, F2, F3) berbentuk pasta, warna coklat muda, bau mint khas mengkudu dan homogen untuk semua formula. Hasil pengujian pH sediaan pasta gigi F1(7,6), F2(7,3), F3(7,2); tinggi busa F1(1,7 cm), F2(1,5 cm), F3(1,4 cm); viskositas F1(2436 cP), F2(2446 cP), F3(2146 cP). Hasil uji stabilitas menunjukkan untuk F1, F2, F3 tidak memisah dan stabil selama penyimpanan 6 minggu. Dapat disimpulkan bahwa ekstrak etanol daun mengkudu 4% (F1), ekstrak etanol daun mengkudu 8% (F2), ekstrak etanol 12% (F3) dapat diformulasikan dalam bentuk sediaan pasta gigi gel dan stabil selama masa penyimpanan.
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