Acalypha indica L. is one of herbal plants found in wet, moderate, tropical areas which grows as a weed. This herb has been used traditionally to treat dysentery, diarrhea, malnutrition, and malaria. But chemical compounds in Acalypha indica L. hasn’t been completely reported yet. This study aims to evaluate chemical compounds and total antioxidant of Acalypha indica L. extract. The extraction of Acalypha indica L. was carried out by maceration method using methanol and ethanol as solvent. The rendemen, water and ash content of Acalypha indica L. extract determined by gravimetric methods. The DPPH method was used to determine total antioxidant and the X-Ray Fluorescence method was used to analyze of the elements contained in the extract. The yield of methanol extract was 14.83%, this was greater than the ethanol extract of Acalypha indica L. which was 5.94%. The water and ash content of the methanol extract were obtained 10.57% and 17.44% respectively, while the ethanol extract was 35.66% and 17.93%. Phytochemical screening of Acalypha indica L. in methanol and ethanol extracts showed that the extracts contained phenolic, flavonoids, steroids, terpenoids and alkaloids compounds. The total antioxidant was obtained 1.59 mg/gDW and 3.11 mg/gDW in methanol and ethanol extract. XRF analysis results showed that methanol and ethanol extract contained elements Mg, Si, Cl, K, Mn and Fe. Based on the result, it can be concluded that Acalypha indica L. extract contained some compounds and elements which is beneficial for health.
AbstrakLebih dari 3 juta orang buta bilateral karena POAG di seluruh dunia, dan lebih dari 2 juta orang mengalami POAG setiap tahunnya. POAG yang tidak terdiagnosis merupakan reservoir terbesar dari kebutaan yang dapat dicegah dimana 30% kasus belum terdiagnosis. Banyak pasien tidak terdeteksi dini dan datang dengan tampilan klinis yang lanjut, mengindikasikan perlunya program intervensi untuk deteksi dini dan perujukan kasus-kasus POAG untuk mencegah kehilangan fungsi penglihatan yang signifikan. Tujuan: Menjabarkan tampilan klinis POAG di RS DR. M. Djamil. Metode: Sejumlah 32 pasien POAG dari 229 pasien glaukoma didapat, dimana jumlah pasien laki-laki (81,3%) lebih banyak dari pasien wanita (18,7%). Umur pasien yang paling banyak ditemukan adalah di antara 51-70 tahun (62,6 %). TIO dari 17,2, 3% pasien adalah di atas 21 mmHg, dan 79,7 % di bawah 21 mmHg. Sebagian besar rasio cup/disc pasien adalah 0,9-1,0. Tampilan perimetri pasien menunjukkan defek altitudinal, defek arkuata, nasal step, temporal island, generalized depression, tunnel vision, dan skotoma perifer. Kesimpulan: Sebagian besar pasien POAG berumur 51-70 tahun, laki-laki, dan datang dengan tampilan klinis yang lanjut Kata kunci: POAG, TIO, rasio cup/disc, perimetri. AbstractEnglish, Arial 9 italic More than 3 million people are bilaterally blind from POAG worldwide, and more than 2 million people will develop POAG each year. Undiagnosed POAG is the greatest reservoir of preventable blindness were more than 50 % of cases have been diagnosed yet. Many patients were not detected early and found in late clinical appearance, indicate the need for an intervention program for early detection and referral of POAG cases in order to prevent significant visual loss. Objective : The aim of our study is to describe clinical features of POAG in Dr.M.Djamil hospital as tertiary referral hospital.Methods : This retrospective study was conducted at ophthalmology department M. Djamil Hospital Padang, from January to Desember 2015. All POAG patients attended were included in the study and collected data included: age, sex, intraocular pressure,cup/disc ratio, and perimetry examination. Result : A total 32 POAG patients of 229 glaucoma patients were included. The number of male patients (81,3 % ) more than the female patients (18,7%). Most common presenting age group was between 51-70 years old (62.6 %). Intraocular pressure of 17,2, 3% patients were above 21 mmHg, and 79,7 % patients had below 21 mmHg. Most of cup/disc ratio of patients was 0,9-1,0. The perimetry appearance of patients revealed altitudinal defect, arcuate defect, nasal step,temporal island, generalized depression, tunnel vision, and peripheral scotoma.Conclusion : Most of POAG patients were between 51-70 years old, male, and came in advanced clinical appearance.
Trauma mata termasuk salah satu kasus kegawatdaruratan bagian mata, jika tidak segera ditatalaksana dapat menyebabkan kebutaan yang menimbulkan kerugian fisik, psikologi, dan sosioekonomi. Tujuan penelitian ini adalah menentukan hubungan jenis kelamin, usia, pekerjaan, lateralisasi, dan visus terhadap jenis trauma mata pada pasien di IGD dan Poliklinik Mata RSUP Dr M Djamil Padang. Jenis penelitian ini adalah analitik dengan desain cross-sectional study. Penelitian ini dilakukan di bagian rekam medis RSUP Dr.M.Djamil Padang mulai bulan Oktober 2017 sampai Februari 2018. Populasi penelitian ini adalah seluruh pasien trauma mata yang datang ke IGD dan Poliklinik Mata RSUP Dr.M.Djamil Padang tahun 2016 dengan sampel minimal sebanyak 51 orang. Analisis statistik yang digunakan adalah Uji Korelasi Lambda. Hasil penelitian ini menunjukkan bahwa sebagian besar trauma mata terjadi pada laki-laki (77,6%), usia 22-45 tahun (27,6%), profesi pelajar (44,7%), unilateral (94,7%) dan menimbulkan kebutaan (64,47%). Diagnosis yang paling sering ditemukan ruptur kornea (21,05%) dan jenis trauma tersering adalah trauma tajam (60,5%). Terdapat hubungan antara usia, pekerjaan, lateralisasi dan visus pasien trauma mata dengan jenis trauma mata, tetapi tidak terdapat hubungan antara jenis kelamin pasien trauma mata dengan jenis trauma mata.
Objective : To determine the Quality of Life glaucoma patients using Glaucoma Symptom Scale(GSS) and Glaucoma Quality Of Life-15 Score (GQL-15) Method : This was a cross sectional study. Subjects were patients diagnosed with primary glaucoma, aged >18 years, and able to fully comprehend the quiz on their regular visits. One hundred glaucoma patients were evaluated for their symptoms using Glaucoma Symptom Scale (GSS), and their ability to perform daily activities using the Glaucoma Quality of Life-15 Questionnaire (GQL-15). We analyze the correlation between the age, sex, visual acuity, medical and surgical treatment to the patients’ quality of life. Results: Data shows that there were significant differences between the visual GSS and the GQL- 15 score among respondents with unilateral blindness, bilateral blindness, and no blindness, which is patients with bilateral blindness have the worsen quality of life. The other GSS and GQL-15 statistical test showed no significant result. Conclusion: Quality of life assesment in glaucoma patient is an essential part to provide the most suitable and convenient treatment both in terms of vision and also improving their quality of life. GSS and GQL-15 were the suitable instrument to asses and determine the Quality of Life glaucoma patient in clinical practice.
AbstrakTrauma mata termasuk salah satu kasus kegawatdaruratan bagian mata, jika tidak segera ditatalaksana dapat menyebabkan kebutaan yang menimbulkan kerugian fisik, psikologi, dan sosioekonomi. Tujuan penelitian ini adalah menentukan hubungan jenis kelamin, usia, pekerjaan, lateralisasi, dan visus terhadap jenis trauma mata pada pasien di IGD dan Poliklinik Mata RSUP Dr M Djamil Padang. Jenis penelitian ini adalah analitik dengan desain crosssectional study. Penelitian ini dilakukan di bagian rekam medis RSUP Dr.M.Djamil Padang mulai bulan Oktober 2017 sampai Februari 2018. Populasi penelitian ini adalah seluruh pasien trauma mata yang datang ke IGD dan Poliklinik Mata RSUP Dr.M.Djamil Padang tahun 2016 dengan sampel minimal sebanyak 51 orang. Analisis statistik yang digunakan adalah Uji Korelasi Lambda. Hasil penelitian ini menunjukkan bahwa sebagian besar trauma mata terjadi pada laki-laki (77,6%), usia 22-45 tahun (27,6%), profesi pelajar (44,7%), unilateral (94,7%) dan menimbulkan kebutaan (64,47%). Diagnosis yang paling sering ditemukan ruptur kornea (21,05%) dan jenis trauma tersering adalah trauma tajam (60,5%). Terdapat hubungan antara usia, pekerjaan, lateralisasi dan visus pasien trauma mata dengan jenis trauma mata, tetapi tidak terdapat hubungan antara jenis kelamin pasien trauma mata dengan jenis trauma mata. Abstract Eye injuries is one of the emergency cases in eye department, in which if not treated immediately, will have a high risk of developing eye blindness with negative physical, psychological, and socioeconomic impacts. The objective of this study was to determine the relationship between gender, age, occupation, lateralization, and vision on the types of eye injuries in emergency patients at the emergency and Ophthalmology polyclinic department in Dr.M.Djamil Hospital Padang. This type of research was analytic with cross-sectional study design. This study was conducted in the medical record Dr M Djamil Hospital Padang from October 2017 until February 2018. Population of this study was all the patients with eye injuries reported at the emergency and the Ophthalmology polyclinic department in 2016 with the minimal amount of samples were 51 patients. The statistical analysis was Lambda correlation measure. The results of this study indicated that most eye trauma occurs in males (77,6%), ages 22-45 years (27,6%), student professions (44,7%), unilateral (94,7%) and cause blindness (64,47%). The most commonly found diagnosis is corneal rupture (21,05%) and the type of trauma is sharp trauma (60,5%). There are significant relationship between the age, occupations, lateralization, and vision of the patients on the types of eye injuries, but there is no significant relationship between gender of the patients with the types of injuries.
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