Midplane dose estimates in vivo using this method provide accurate determination of delivered dose in the middle-third esophagus RT treatments. This method could be useful in similar clinical circumstances for dose confirmation and documentation.
The purpose of this study was to conduct quality assurance of a three dimensional conformal radiotherapy (3DCRT) of two targets in pelvis region planned with single isocenter technique. Methods: A treatment plan was generated with two identical water phantoms with ionization chamber (IC) sleeves (IC-1 & IC-2), simulated as if targets are in pelvis region, simultaneously irradiated with single isocenter technique with a dose prescription of 300 cGy for point dose verification. A two dimensional ion chamber array detector was used for fluence verification. Results: Calculated minimum, mean and maximum dose (in cGy) for IC-1 & IC-2 were 295, 303 and 307 as per dose volume histogram. The global dose maximum was found to be 307.4 cGy. Measured point doses to both lesions were within ±2.5% of the computed dose. A pass percentage of 97% was obtained with the set of criteria 3 mm distance to agreement and 3% dose difference for fluence verification. Conclusion: Treatment execution of two targets simultaneously with single isocenter can reduce positional errors and delivery time.
Background: The various advantages of Fine-needle aspiration (FNA) biopsy/ cytology can be limited due to inadequacy of the specimen and expertise required for diagnosis. Cell blocks (CBs), though routinely used in cytology of body fluids, can also be used in FNA material with considerable increase in diagnostic accuracy. Aims & objectives: To compared FNA & CB as diagnostic tool and to evaluate whether cell block adds to the diagnostic accuracy of FNA.
Methods: This is a two years prospective study carried out in the pathology department of a tertiary heath care hospital and medical college of South India which included the cases undergoing the FNAC, and followed by the biopsy. CB was prepared using Tissue coagulum clot (TCC) method. The smears and tissue sections were assessed for cellularity and adequacy for diagnosis. CBs were grouped into four diagnostic categories. FNA & CB were compared with histopathology (HPE) diagnosis to calculate Sensitivity, Specificity and Diagnostic Accuracy.
Result: A total of 195 cases were included. Cellularity and adequacy for diagnosis were higher in CB. They were diagnostically better (superior) in 13.84% (27) cases. The sensitivity (95.77%) and diagnostic accuracy (94.87%) of CB was found to be considerably higher than FNA (78.84% and 78.46% respectively).
Conclusion: In cases of suspicious/ intermediate diagnosis or diagnosis discordant with clinical ones, by FNA; should be followed with the CB to improve the diagnostic yield & to facilitate accurate diagnoses. TCC method is a simple CB method which has higher diagnostic accuracy than FNA.
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