Multiple research studies have examined the role of specific dietary interventions and their effects on skin barrier function. The skin barrier is one of the body's first lines of protection against environmental insults, and disruption of this natural line of defense can result in xerosis, irritation, chronic dermatitis, and other cutaneous effects. Multiple laboratory, animal, and human studies have demonstrated that certain dietary interventions have the potential to impact skin barrier function. Measurements of skin barrier function include stratum corneum hydration and transepidermal water loss. In this review, we examine this research and provide an overview of the effects of prebiotics, probiotics, fatty acids, and emerging research on other substances.
Background: Dietary supplements are popular among US consumers and claim to address a variety of conditions, including acne. Acne supplements containing vitamin A are of particular interest, due to the potentially teratogenic effects of vitamin A doses over 10,000 IU. Objective: This study examined dosage, pregnancy risks, and labeling of vitamin A-containing acne supplements available online. Methods: An Internet search of acne supplements sold online was conducted between March and May 2020. Supplement labels and websites were analyzed for vitamin A content and pregnancy warnings, and then divided into categories based on dosage and teratogenic risk. Results: A total of 49 acne supplements was found, and of these 26 (53%) contain vitamin A. Three supplements are likely teratogenic, 4 contain vitamin A doses exceeding the daily level of intake that meets the nutritional needs of most people, and 15 have an unknown teratogenic risk. Among the 6 supplements with over 10,000 IU vitamin A, 2 have no pregnancy warning at all, including the supplement with the highest vitamin A dose found in this study. Conclusions: Dietary supplements are not subject to the same stringent regulations as drugs, and as such, consumers may be unaware of pregnancy risks. Furthermore, FDA requirements on labeling of vitamin A supplements may lead to consumer confusion regarding dosage. As such, we encourage stricter labeling requirements for vitamin A-containing supplements, including pregnancy warnings for high-dose supplements and clearer dosage labeling.
Rice is not a new ingredient in skin and hair care, given that domestication of modern-day rice occurred approximately 10,000 years ago.There is great debate over the origins of modern-day domesticated rice, as genetic data cannot pinpoint whether it was first domesticated in East Asia, the Indian subcontinent, or both. 1 There are various anecdotes regarding the cosmetic uses of rice throughout the beauty industry. In one such story, elderly workers in a fermented rice wine brewery were said to have wrinkle-free hands.Further exploration resulted in the discovery of Pitera, a powerful anti-wrinkle ingredient used in various cosmetics. 2 Similar tales exist surrounding the practices of the Japanese court women of the Heian Period. These women used water obtained from rinsing of rice for their hair care. Scientific studies of this "rice water" found that it increased hair elasticity and reduced surface friction. 3 A quick Google search for "rice skin care products" yields 133 million hits, leading to a multitude of online stores and articles that recommend various cleansers, exfoliating mixtures, essences, and creams that are obtained from rice. Many of these websites claim that said products are recommended by dermatologists. In this article, we explore the components of rice and the dermatological benefits that make rice such a popular cosmetic ingredient. Additionally, we discuss the safety of its use. | COMP ONENTS OF RI CE AND DERMATOLOG IC AL B ENEFITS | Phenolic compoundsPhenolic compounds, found in jasmine rice panicle extract and rice brain, confer important antiaging properties. [4][5][6][7] One study of rat dermal fibroblasts found anthocyanin, a phenolic compound present in black rice, to be a promising antiaging and anti-inflammatory compound. 8 Even ingested rice enriched with the polyphenol resveratrol
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