Systemic Lupus Erythematosus (SLE) is an autoimmune disorder which affects multiple organs of human including lungs.To assess FVC, FEV 1
Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disorder which affects multiple organs of human including lungs. Objectives: in SLE patients and to correlate them with the duration of the disease. Method: This cross-sectional study was carried out in the Department of Physiology, BSMMU, Dhaka, from January 2010 to December 2010. A total number of 120 female subjects were selected, among which 30 were age and BMI matched apparently healthy subjects for comparison (control) and 90 were patients of SLE (study group). All the patients were matched for age, sex and BMI. Based on the duration of the disease, patients were subdivided into B1 (1-6 months), B2 (2-5 years) and B3 (6-10 years). Controls were selected from the community and the patients from the Out Patient Department (OPD) of SLE clinic, Department of Medicine, BSMMU, Dhaka. (PEFR) and FEF 25-75 of all the subjects were measured by a Digital MicroDL spirometer. For statistical analysis Independent Sample 't' test, One way ANOVA test and Pearson's correlation coefficient test were performed as applicable. Results: The mean percentage of predicted values of lung function parameters in healthy female subjects were within normal ranges. The mean percentage of predicted values of PEFR and FEF 25-75 were significantly lower in all study groups when compared to control. Again, the mean percentage of predicted values of PEFR and FEF 25-75 were significantly lower in the patients of Group B3 compared to Group B2. Moreover, these comparisons were significantly lower when compared to Group B1. The differences of the mean percentage of predicted value of PEFR, FEF 25-75 were non-significantly lower in Group B2 when compare to Group B1. In addition, FEF 25-75 were positively correlated with duration of SLE in group B2 but negatively correlated in B3. On the other hand PEFR was negatively correlated with duration of SLE in both B2 and B3. All these values were statistically non-significant. Conclusion: These pulmonary functions decrease in SLE female and the reduction is inconsistently associated with duration of the disease.
Background & Objectives: Mizaj (Temperament) of a person is given great importance for identifying the most suitable diet and lifestyle for promoting the health of a particular individual. On the basis of Mizaj human beings have been categorized into four qualitative types: Damvi, Balghami, Safravi, and Saudavi. So the main aim of this study was to an analytical study of renal function in healthy young adults of different temperament. Methods: This was an observational study. Fifty healthy volunteers were selected as per inclusion and exclusion criteria and allocated into four groups as per Ajnas-E-Ashra. The patients of all Mizaj categories were assessed for renal function tests of blood urea, serum creatinine and Glomerular Filtration Rate (GFR) along with demographic description for age, gender, occupation, religion, weight, etc. Results: The study found that 11subjects were of Mizaj Damvi, 26 Balghami, 12 Safravi, and one of Saudavi. There was marked differences in various parameters when analyzed in consideration with Mizaj categories. Renal function parameters also varied in respect of Mizaj categories though they were in normal range. Conclusion:The Study showed that there were variations in various demographic parameters and renal function tests in various Mizaj categories.
Background: HBeAg status in chronic hepatitis B patients is important for outcome and treatmentObjective: The purpose of the present study was to see the status of HBeAg Chronic Hepatitis B (CHB) patients.Methodology: This cross sectional study was conducted in the Department of Virology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka between July 2010 to June 2011. Serologically diagnosed CHB patients were enrolled for the study. The HBV DNA was quantified. Samples were tested for HBeAg with ELISA kit.Results: A total of 200 serologically diagnosed CHB patients were enrolled for the study. Among the total study population, HBeAg positive CHB patients were 74(37%) cases and HBeAg negative patients were 126 (63%) cases. Among the HBeAg negative patients, viral load was less and patients were significantly older. The mean viral load of HBeAg positive and HBeAg negative was 64012042 and 2.83i2.55 respectively. HBV DNA was a more reliable indicator of the presence of virus than HBeAg, and was detected in 98.65% (73/74) HBeAg positive carriers, and in 66.67% (84/126) HBeAg negative patients.Conclusion: HBeAg negativity is more prevalent among the CHB patients in Bangladesh.J Shaheed Suhrawardy Med Coll, 2014; 6(2):60-63
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