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COVID-19 diagnosis-a fatal disease-may have contributed to the trigger. We did not find any reports that azithromycin may exacerbate psoriasis. 8 There were no reports of any severe cases of COVID-19 infection linked to biological agents, and we administered ustekinumab 90 mg sc to our patient effectively. 9 Further studies will guide whether hydroxychloroquine is indeed a single trigger or initiator in the etiopathogenesis of psoriasis.

Lichen nitidus is an uncommon lichenoid dermatosis that could be defined as multiple, separated, shiny, pinpoint, pale to skin-colored papules. Palmoplantar lichen nitidus is a quite rare variant of lichen nitidus. It is hard to make a diagnosis of palmar lichen nitidus when there are no lesions elsewhere on the body. There are some dermoscopic features defined for both palmoplantar and non-palmoplantar lichen nitidus that might be useful to facilitate the diagnosis before histopathological examination. Herein, we report a case of a 24-year-old man diagnosed with isolated palmar lichen nitidus with dermoscopic features and histopathological confirmation.

The present study investigates the relationship between psoriasis and diseases such as health anxiety, depression, and somatosensory amplification. MethodsThe participating patients (n=117, including 60 psoriasis patients and 57 controls) filled out the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Somatosensory Amplification Scale (SSAS), and Health Anxiety Inventory (HAI) questionnaires. ResultsThe mean scores from SSAS, HAI, and BDI were significantly higher in the psoriasis group than in the control group (p<0.05 in all comparisons). When the group medians of BAI were evaluated, the differences were not statistically significant, although BAI medians were higher in the patient group. Furthermore, a moderate correlation was found between the involvement of specific areas (especially the scalp and face) and SSAS scores. ConclusionPatients with psoriasis score highly in depression, health anxiety, and somatosensory amplification, and there was a moderate correlation between specific body area involvement (especially the scalp and face) and SSAS score. The results of this study seem to indicate that psychiatric assessment and treatment approaches should be included in the treatment of such chronic skin diseases as psoriasis that follow a life-long remission and relapse pattern.

Grief mania that is evaluated as psychogenic mania in the literature is related to manic episode that emerges after the loss of a loved one. There are not many cases that associate causality of beginning of mania and mourning in the literature. It is known that mania is induced by traumatic events but the cases that do not suit stages of development of grief process are evaluated as pathological grief. In this case, the woman who experienced manic episode after her son's death is presented. This case is prepared because mania should be considered as possible grief reaction. Case presentation: A patient who is 40 years old, married, mother of 4 children is brought by relatives because of aggressiveness, tension, insomnia for 4 days, fast and talk a lot and nonsense laughing attacks. She was presented to hospital for stressful life events 2 years ago and started to be on medication (escitalopram 10 mg) because of depression and fibromiyaliji diagnosis. She used medication for 1.5 years and she did not use any medication for the last 6months. There is no history for mental disorder in her family. Psychological examination: her interest for the environment was increased, self-care ability got better, her temperament was cheerful, her sociability was respectful, amount of talking and tone of voice increased, mimic and gesture was appropriate for her temperament, sleeping decreased, thought flow increased and achieved goal of conversation late. Moreover, there were grandiose delusions and hypervigilance, affect was close to euphoria, her psychomotor behaviours increased and social functioning decreased. According to biochemical and radiological workup, there was no pathological situation. The client started to use Lithium 900 mg/day and Olanzapin 10 mg/day because of the bipolar disorder diagnosis. The patient's blood lithium level was 0.8mEq/L and lithium was used 1200 mg/day and then 10 days later the patient's blood lithium level was 0.72 mEq/L. According to clinical observations, the patient's manic symptoms remained. Furthermore, the patient started to cry occasionally after 1 month and her grandiosity disappeared. The patient was discharged from the hospital after 45 days. The patient met the criteria for manic episode in DSM 5. The patient did not take any medication for last 6 months. Thus, it is considered that this situation was not induced by medication. It puts the patient into risk group because she was treated for depression before but it is not considered as bipolar depression because there were psychiatric history in the family and depression that experienced 2 years ago was related to stressful life events. It is considered that this case experienced grief/funeral mania because there was contiguity between loss of her son and manic episode, the patient did not react this way to previous challenging life events and the patient was outside of the ordinary 5 stages of grief process.

Öz Bu çalışmada asmada Botryosphaeria Geriye Ölüm Hastalığı etmenlerinden Neofusicoccum parvum türünün Tarsus bağlarındaki yaygınlığı ve bölgede yetiştirilen bazı sofralık üzüm çeşitlerinin patojene duyarlılıklarının araştırılması amaçlanmıştır. Ağustos 2018'de Tarsus'a bağlı 12 farklı köyde 50 bağ incelenmiş, simptomatik asmaların varlığına göre hastalık yaygınlığı hesaplanmış ve fungal izolatları elde etmek için hastalık belirtisi gösteren asmalardan odunsu doku örnekleri alınmıştır. Laboratuvarda standart mikolojik izolasyon yöntemleri takip edilmiş, Botryosphaeriaceae türlerine benzeyen koloniler saflaştırılmıştır. İzolatlar moleküler yöntemlerle tanılanmış ve Neofusicoccum parvum izolatları ile patojenisite çalışmaları yürütülmüştür. En virülent iki izolat çeşit duyarlılığı çalışmaları için seçilmiş, bunlar bölgede yaygın yetiştirilen 11 asma çeşidine inokule edilmiş ve odunsu dokularda oluşan lezyonlara göre çeşitlerin duyarlılık seviyeleri belirlenmiştir. Sonuçlara göre, hastalığın Tarsus'taki yaygınlığının %14 olduğu saptanmış ve laboratuvar çalışmalarında 21 Botryosphaeriaceae izolatı elde edilmiştir. Moleküler tanı çalışmalarıyla bu izolatlardan %61.9'unun Diplodia seriata, %23.8'inin Lasiodiplodia pseudotheobromae, %14.3'ünün Neofusicoccum parvum ve %4.8'sinin Lasiodiplodia theobromae olduğu bulunmuştur. Patojenisite denemesi sonunda, en virülent N. parvum izolatları (49 ve 103) asma bitkilerinde 12.5-20.5 mm arasında değişen uzunluklarda odun doku lezyonlarına neden olmuşlardır. Çeşitlerin bu izolatlara karşı duyarlılığı birbirinden farklılık göstermiş, bunların duyarlılık sıralamaları birebir aynı olmamıştır. N. parvum izolatları inokule edildiğinde en tolerant üzüm çeşidi 12.5 ve 13.1 mm'lik lezyon uzunluklarıyla Cardinal çeşidi olmuştur. 49 nolu izolatın oluşturduğu lezyonlar çeşitler üzerinde istatistiksel olarak küçük farklar meydana getirmiş ancak 103 nolu izolatın oluşturduğu istatistiksel gruplar geniş aralıkta olmuştur.

Risperidone is an atypical antipsychotic that antagonizes 5HT2A and D2 receptors. Risperidone is used for many indications in children and adolescents. These indications include bipolar mania, schizophrenia, disruptive behaviour disorders, and aggression associated with autism spectrum disorder/mental retardation. Although it is usually well tolerated, weight gain, somnolence, rhinitis, headache, and rising appetite are among the most noticed side effects. Here we present a 5-year-old boy who developed diffuse nonpruritic maculopapular skin rash with a stable dosage of risperidone in the eighth month of treatment. ARTICLE HISTORY

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