People in Indonesia often consume food containing sucrose. If the sucrose consumed is in a large amount, it will decrease saliva's pH and soon teeth destruction will happen. To avoid it, it is necessary to change sucrose consumption habit into another kind of sugar, namely sorbitol. Sorbitol is preferred to use, because it is cheaper and easier to get. Sorbitol is made from cassava, which is plentifully grown in Indonesia. Sorbitol is not good media for bacteria to grow. Because sorbitol has a diol, so it's difficult to catalyst by glucosyltransferase enzyme, which is produced by bacteria Streptococcus mutans. The conclusion is that sorbitol is difficult to be fermented by Streptococcus mutans so it will not decrease saliva's pH.
Introduction: The purpose of a restoration is to restore the shape, function, and phonetics and aesthetics of damaged teeth. The disadvantage of direct composite restorations is the formation of dental anatomical structures that require operator skills so that they can optimally restore tooth occlusion. Case report: Case 1: A 21-year-old female patient with D4 caries, Site 1 size 2 on tooth number 37 and the patient's dental diagnosis was Reversible Pulpitis. The patient was treated with a composite restoration using the stamp technique. Case 2: A 50-year-old male the patient with D5 caries, Site 1 Size 2 on tooth number 46 and patient’s dental diagnosis was Irreversible Pulpitis. The patient was treated with a composite restoration using the pizza technique. Conclusion: Stamp technique is indicated for hidden caries in pits and fissures or proximal parts of the tooth with intact anatomical forms. The pizza technique can be used in caries with incomplete anatomical forms but requires operator skills to form biomimetic dental anatomy.
<p><strong>Background:</strong> <em>Corticosteroid has a strong anti-inflammatory effect, unfortunately long-term usege of corticosteroid drugs can suppressed immune system. This condition makes Candida albicans as an opportunistic phatogen caused Oral Candidiasis. Macrophages have an important role in the first defense against infection. Methanol extract of A.ilicifolius leaf has anti-fungal, anti-inflammatory compounds to fight the growth of Candida albicans. <strong>Purpose:</strong> To determine the effect of methanol extract of A.ilicifolius leaf theraphy to the amount of macrophages in the healing pricess of oral candidiasis models with immunosuppressed conditions. <strong>Method:</strong> </em><em>This study was true experimental with post test only control group design. Thirty-six strain wistar, 3 months old, and 250 grams of weight which were given dexamethason 0.5 mg and tetracycline 0.5mg for 7days, after Candida albican(ATCC10231) was induced for 2 weeks (3 times/week). Rats were divided into 6 groups: untreated(K-), nystatin(K+), A.ilicifolius 8%(P1), A.ilicifolius 12%(P2), A.ilicifolius 16%(P3), A.ilicifolius 20%(P4 ) all groups were treated for 2 weeks. After being treated, the rats tongue biopsied to examine the macrophages with Haematoxylin-eosin staining and observed with microscope (400x magnification). Data analyzed statistically by One-way ANOVA. <strong>Results:</strong> the amount of macrophages at K+(47.60±4.16), P4(40.20±3.56), P3(36.20±1.92), P2(17.00±2.45) were greater than K-(15.60±4.56), P1(14.60±2.70). there are no significant difference between group K- with P1 and P2, P3 with P4. There are significant difference between group K- with K+, K- with P3 and P4. K+ with P1, P2, P3 and P4. Group P1 with P3 and P4. Group P2 with P3 and P4. </em></p><strong><em>Conclusion:</em></strong><em> A.ilicifolius extract can increase the amount of macrophages in oral candidiasis immunosuppression models</em>
<p><strong><em>Background:</em></strong><em> Dental and oral diseases which </em><em>a</em><em>re often found in children is dental caries. Streptococcus mutans </em><em>i</em><em>s the main cause of caries. Caries c</em><em>an</em><em> be prevented by using a topical application of fluoride. The Anchovy (Stolephorus insularis) contain</em><em>s</em><em> protein, vitamins (A, B<sub>1</sub>, C), and minerals (Fe, Ca, K, F). Calcium fluoride (CaF<sub>2</sub>) within the anchovy c</em><em>an</em><em> inhibit the occurrence of dental caries. <strong>Purpose</strong></em><strong><em>: </em></strong><em>The aim of this study was </em><em>to </em><em>determine the </em><em>antimicrobial </em><em> ability of anchovy extract (Stolephorus insularis) to Streptococcus mutans. <strong>Materials and</strong> <strong>Methods: </strong>This study was a laboratory experimental research </em><em>with</em><em> post test only control group design. Diffusion method were applied with 2 controls: negative control used DMSO 1%, positive control used NaF solution, and 3 concentrations of anchovy extract (Stolephorus insularis) 3%, 6%, and 12%, each group were composed of 6 samples. </em><em>Antimicrobial</em><em> was assessed by measuring the diameter of the clear zone around the discs contained the anchovy extract (Stolephorus insularis). Data were analyzed by Kruskal-Wallis test followed by Mann-Whitney test.<strong> Result:</strong> The results from this study showed clear zone around the discs of the anchovy extract (Stolephorus insularis). The more concentration of the extract showed the more </em><em>antimirobial</em><em> zone diameter. The average zone of </em><em>antimicrobial</em><em> at </em><em>the </em><em>concentration of 3% </em><em>were </em><em>7,11 mm, 6%</em><em> </em><em>9,5 mm, 12%</em><em> </em><em>10,78 mm, for the negative control DMSO 1% 6 mm and the positive control NaF solution 8,16 mm. The largest diameter of the clear zone was at concentration of 12% (P < 0,05).</em><em> </em><strong><em>Conclusion: </em></strong><em>The<strong> </strong>anchovy extract (Stolephorus insularis) had an antimicrobial effect to the growth of Streptococcus mutans.</em><em></em></p>
Background: Streptococcus mutans in the most frequent microbiota that causes pulp necrosis because of caries. The microorganism that is colonized and embedded in the biofilm matrix is resistant to antimicrobials compared to planktonic cells. Root canal sterilization materials must have good biocompatibility with tissues. Nannochloropsis oculata is an algae that contains various compounds such as terpenoids, alkaloids, and flavonoids that have potential as antibacterial and antioxidant and can be used as alternative to root canal sterilization. Method: This research was true experimental laboratory research with post-test only control group design. The antibacterial potential of Nannochloropsis oculata was tested using the biofilm method, divided into 5 groups. The control group was: K- (aquadest), K+ (calcium hydroxide), and the treatment group was given Nannochloropsis oculata: P1 (0.625%), P2 (1.25%), and P3 (2.5 %). Congo Red method test was to determine the formation of biofilm that shows black strains on agar. While biofilm test with Microtiter Plate Assay to measure the value of biofilm that were inhibited in Optical Density (OD) value in the ELISA Reader. The lower the value, the more biofilm inhibited, with OD value, inhibition percentage could counted Result: The result of all treatment groups were increasing in percentage inhibition value shows inhibition in biofilm growth (p <0.05). Conclusion: Nannochloropsis oculata had an antibacterial effect on the biofilm of Streptococcus mutans
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