Anthocyanins are the flavonoid derivatives; widespread in the plant kingdom; imparting most of the brilliant colours like orange, red, pink, purple and blue; observed mostly in fruits, flowers and leaves (Zheng et al., 2011). Some of the naturally occurring anthocyanins of plants are cyanidin, peonidin, malvidin, delphinidin, pelargonidin and petunidin (Liliana et al., 2012). Chemically, the anthocyanin has a flavylium nucleus attached to one or more sugar residues, which may be Dglucose, D-galactose, L-rhamnose, D-xylose, and D-arabinose, are 3-glycosides or 3,5-di-glycosides (Miguel, 2011). Apart from being a natural colorant, anthocyanins have gained considerable research interest due to health benefits shown as a results of their antioxidant properties. Several times, antioxidants activity of anthocyanins have been demonstrated using several models (Miguel, 2011). Lantana camara L. (Figure 1) is an ornamental but notorious weed belong to family Verbenaceae (Patil and Kumbhar, 2017). It bears the flowers of colour ranging from yellow-white or pink to deep red or purple. (Huang et al., 2009) proved the presence of pigments, identified as 3-glucoside, 3,5-diglucoside and 3malonylglucoside of cyanidin, and 3,5-diglucoside and 3-malonylglucoside of peonidin in flowers (Huang et al., 2009) (Figure 2). An acid-base indicator is a compound which changes color according to change in pH. For synthetic acid-base indicators, it has been reported that they may have carcinogenic effect (Dunnick and Hailey, 1996). In addition, some of these synthetic indicators exhibited toxic effects such as pulmonary edema, diarrhea, hypoglycemia and pancreatitis and they can result in abdominal cramps, skin rash, eruptions, erythema, and epidermal necrosis and cause environmental pollution (Pathade et al., 2009; Abugri et al.,
Introduction: Formation of cavities and hyper sensitivity are few dental problems, manifested by dental pain. Since long back, volatile oil present in clove buds (Myrtaceae) have been used as dental analgesic. Various toothpastes containing clove oil are marketed. Eugenol is chemically, terpenoids, active principle present in clove oil. It has several pharmacological potentials. Pro-argin technology is novel approach for formulation of toothpaste with arginine (8%) and calcium carbonate. Aim: This research was aimed towards formulation of toothpaste containing eugenol by Pro-argin technology and its evaluation. Materials and Methods: Toothpaste containing eugenol was formulated with arginine (8%) and calcium carbonate by simple trituration. Formulation was then evaluated for various parameters like pH, spreadability, foaming ability, content determination and also analysed for texture. Results and Discussion: On formulation, brownish, aromatic fragrant toothpaste was obtained with acceptable pH, spreadability and foaming ability. About 92.48% of eugenol content of added quantity was determined. Conclusion: Eugenol can successfully be formulated in toothpaste by Pro-Argin approach. More than 90% content determination would facilitate maximum release of added eugenol.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.