Rice cracker or known as Krupuk puli is the kind of deep-fried crackers in Indonesia that made of rice seasoned with spices and flavor enhancer. Most Rice cracker sellers that peddle their products in the Ngunut traditional market, so that the sellers have to make or prepare the rice cracker as well as possible to make the cracker can be sold. In this case, most manufacturers add hazardous materials (borax) in the process of making rice crackers. The purpose of this research is to validate the method and to know the borax level of rice crackers sold in the Ngunut traditional market by using the UV-Vis spectrophotometry method. Optimization of borax wavelength in the wavelength range of 500-600 nm. The prepared samples are analyzed using UV-Vis spectrophotometry at the maximum wavelength that is 506 nm. The next step, is, validation methods, including linieritas test, accuracy test, precision test, and LOD test & LOQ. The result of this study obtained the optimum wavelength is 506 nm. Based on the validation methods that have been done, obtained the results of inference linearity in the concentration range of 5ppm; 20ppm; 35ppm; 50ppm; 65ppm with a physical value of R2 correlation of 0.993,%recovery by 96.5%, the precision value obtained by 0.375%, and the LOD value of 48.565 ppm amounting and a Loq value of 161.381 ppm. The borax level in sample A amounted to 1,380 ± 1.824 ppm, sample B of 852.1 ± 2.367 ppm, sample C of 1,373 ± 1.824 ppm, and sample D of 185.9 ± 1.788 ppm.
Diabetes adalah salah satu penyakit tidak menular dan bersifat kronis serta prevalensinya cukup tinggi di Indonesia bahkan Dunia. Penyakit ini ditandai dengan peningkatan kadar gula darah acak ≥ 200 mg/dl. Kadar gula darah yang tinggi dan tidak terkontrol dapat menyebabkan berbagai komplikasi sepert gagal, ginjal, stroke, neuropati dan lain sebagainya. Salah satu strategi dalam kontrol gula darah selain mengontrol asupan makanan adalah juga dengan mengkonsumsi obat antidiabetes secara rutin sesuai dosis. Salah satu masalah dari penggunaan obat adalah pengetahuan yang rendah serta “lupa” yang sering menjadi faktor yang mengurangi kepatuhan pasien dalam mengkonsumsi obat antidiabetes. Untuk meningkatkan pengetahuan maka salah satu yang bisa dilakukan adalah dengan penyuluhan dan mengurangi faktor lupa dapat menggunakan pillbox. Pengabdian ini terbagi menjadi 4 tahapan. Tahap pertama adalah melakukan pengukuran pengetahuan dan kepatuhan warga, tahap ke empat juga melakukan pengukuran pengetahuan dan kepatuhan warga setelah adanya pengabdian dengan menggunakan kuesioner. Setelah akhir pengabdian, data dianalisis dengan Shapiro-Wilk dilanjutkan uji Willcoxon karena data tidak terdistribusi normal untuk mengetahui perbedaan pengetahuan dan kepatuhan sebelum dan sesudah pengabdian ini. Dari hasil pengabdian ini tidak terdapat perbedaan yang signifikan terhadap nilai pengetahuan sebelum 79,78 ± 3,90 sesudah 80,38 ± 4,63 dengan p-value > 0,05, akan tetapi terjadi peningkatan nilai kepatuhan sebelum 22,90 ± 4,01 dan sesudah 15,98 ± 2,84 dengan p-value < 0,05.
Increasing age can cause a variety of degenerative disease, one of which is hypertension. One issue is the treatment of geriatric poiypharmacy the drug interactions may pose clinical problems that require a carefui monitoring and action, for exampie the use of antihypertensives. This study aims to determine the picture of drug use and the reiationship between the number of medication and comorbidities withpotential drug interactions. This study is an observational analytic study using cross sectional study design. Data is retrospectively col lected by using affordable population that meet the cn'teria. The determination of the relationship between the amount of active drug substance and thenumberof comorbidities, with the potential for drug interactions are analyzed using a linear regression. The results show that the most widelyprescribed antihypertension research is in the singular (35.47%) ofamlodipine (46.37%), about 51.27%) of the recipes contain a potential for drug interaction, with the potential drug inter
Background: Drug related problems (DRP) can cause problems in treatments of patients with ischemic stroke. Objective: This study was to determine the correlation between the characteristics of patients with ischemic stroke and the DRP. Methods: A population in this study was 53 patients at dr Iskak Public Hospital in Tulungagung. Inclusion criteria were patients who were ≥ 60 years old and were diagnosed as acute ischemic stroke patients. The DRP was classified based on Pharmaceutical Care Network Europe version 6.2, especially problem and cause domain. Correlation between age, duration of treatment, number of comorbidities and number of drugs and the DRP was analysed by Spearman Rho or by Pearson analysis. The relationship between gender, guaranteed care and the DRP was analysed by using Eta analysis.Results: This study revealed that patients with 60-69 years were 24 patients (45.28%), men were 30 patients (57%), 1 comorbidity was 26 patients (49.06%), duration of 5 days was 14 patients (26.42%), BPJS patients were 23 patients (35.94%), using 6 types of drug was 11 patients (20.75%). Age, sex and care guarantee did not correlate with the DRP (p-values > 0.05). Duration of treatment, number of comorbidities and number of drugs correlated with the DRP (p-value <0.05) with consecutive correlation strength: weak (R = 0.32), moderate (R = 0.45), strong (R = 0.56). Conclusion: Duration of treatment, number of comorbidities and number of drugs correlated with increasing incidences of the DRP in geriatric ischemic stroke patients.
Cesareans antibiotic prophylaxis aims to prevent the clinical manifestations of SSI expected to occur. Theoretically, Cefazoline is considered more advantageous as a cesarean prophylactic antibiotic than Ceftriaxone. This study aims to compare the effectiveness of Cefazoline and Ceftriaxone as cesarean prophylactic antibiotics at RSIA Trisna Medika Tulungagung from October–December 2021. The study used a cross-sectional research design using 214 medical records data of patients with preoperative prophylactic antibiotics Cefazoline and Ceftriaxone (1:1). Data analysis includes antibiotic use profiles and therapeutic effectiveness data. Statistical analysis used the Mann-Whitney U Test. Research results showed that Cefazoline and Ceftriaxone have the same effectiveness as cesarean prophylactic antibiotics at RSIA Trisna Medika Tulungagung October – December 2021 based on pulse frequency, breath frequency, 10d post-op wound pain, purulent, dry wound, SSI, and LOS.
Lanjut usia adalah seseorang yang berusia lebih dari 60 tahun. Lanjut usia mengalami hipertensi apabila tekanan darahnya mencapai lebih dari 130/80mmHg. Potentially inappropriate medications didefinisikan sebagai obat dengan peningkatan risiko obat yang tidak dikehendaki, yang harus dihindari pada lanjut usia. Beers criteria adalah salah satu instrumen yang digunakan dalam penyesuaian obat yang tidak sesuai, perlu pertimbangan dengan hati-hati maupun perlu dihindari dalam peresepan untuk populasi lanjut usia. Penelitian ini bertujuan untuk melihat bagaimana hubungan antara sosiodemografi dengan kejadian Potentially inappropriate medications dan kesesuaian terapi menurut beers criteria 2019. Penelitian ini menggunakan metode cross-sectionalsecara retrospektif dari data rekam medik pasien hipertensi lanjut usia di instalasi rawat inap RSUD Mardi Waluyo Blitar periode 2021 dan menggunakan metode deskriptif untuk menentukan adanya penggunaan obat yang termasuk dalam daftar beers criteria tahun 2019. Hasil dari penelitian ini menyatakan bahwa kejadian Potentially inappropriate medications berhubungan dengan lama perawatan dengan nilai Sig 0,018 dan jumlah penyakit penyerta dengan nilai Sig 0,047, serta peresepan obat yang tidak sesuai pada pasien lanjut usia penderita hipertensi di instalasi rawat inap RSUD Mardi Waluyo Blitar pada periode 2021 masih tinggi. Kesimpulan penelitian ini adalah obat yang paling banyak digunakan adalah ranitidine dan obat antihipertensi yang paling banyak digunakan adalah furosemide.
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