Analisis Efektivitas Cefazoline dan Ceftriaxone sebagai Antibiotik Profilaksis Bedah Sesar di RSIA Trisna Medika Tulungagung Periode Oktober–Desember 2021

Abstract

Cesareans antibiotic prophylaxis aims to prevent the clinical manifestations of SSI expected to occur. Theoretically, Cefazoline is considered more advantageous as a cesarean prophylactic antibiotic than Ceftriaxone. This study aims to compare the effectiveness of Cefazoline and Ceftriaxone as cesarean prophylactic antibiotics at RSIA Trisna Medika Tulungagung from October–December 2021. The study used a cross-sectional research design using 214 medical records data of patients with preoperative prophylactic antibiotics Cefazoline and Ceftriaxone (1:1). Data analysis includes antibiotic use profiles and therapeutic effectiveness data. Statistical analysis used the Mann-Whitney U Test. Research results showed that Cefazoline and Ceftriaxone have the same effectiveness as cesarean prophylactic antibiotics at RSIA Trisna Medika Tulungagung October – December 2021 based on pulse frequency, breath frequency, 10d post-op wound pain, purulent, dry wound, SSI, and LOS.

Analisis Efektivitas Biaya Penggunaan Antibiotik Profilaksis Cefazoline Dan Ceftriaxone Pada Pasien Bedah Sesar Di RSUD Dr Soedomo Trenggalek

“…Sekitar 90% morbiditas pasca operasi disebabkan oleh infeksi Luka Operasi (ILO) (Hardiyanti, 2020). Antibiotik profilaksis bedah sesar merupakan antibiotik yang diberikan pada wanita yang menjalani prosedur bedah sesar sebelum adanya tanda dan gejala suatu infeksi dengan tujuan mencegah terjadinya manifestasi klinik infeksi yang diduga bisa terjadi (Harwiyanti et al, 2022). Dalam pengobatan bedah sesar ini antibiotik profilaksis yang digunakan yaitu antibiotik cefazoline dan ceftriaxone.…”

Risk Factors Associated with Surgical Wound Healing in Orthopedic Surgery Patients at The Dr. H. Moch Ansari Saleh Banjarmasin General Hospital

“…According to research done at a few hospitals in Indonesia, the frequency of surgical site infections (SSIs) varied from 5.32 to 13.9% for both clean and clean-contaminated procedures (Syaiful, Yarman , Prasetyo, & Toar, 2020). Dry wounds were linked to a higher risk of surgical wound infections in earlier studies (Harwiyanti & Nugraha, 2022).…”

“…If the healing process proceeds according to plan, but if there are any signs of infection or delayed healing, the wound may also be considered chronic. Wound healing becomes problematic if the number of bacterial colonies grows to the point where critical colonization occurs in infection situations (Harwiyanti & Nugraha, 2022). In addition to the psychological, social, and physical effects, lost productivity at work and high-cost medical procedures for wound care put a financial strain on the healthcare system.…”