Delayed surgical closure following VAC therapy may be associated with shorter hospitalization and lower mortality in patients with deep sternal wound infection. Additional operation, diabetes mellitus, and a high level of EuroSCORE were associated with mortality.

This study indicates that effective doses (10 and 20 mg/kg, daily) of the antiplatelet agent ticagrelor in a rabbit model may be beneficial in prevention of intimal hyperplasia. Restenosis due to intimal hyperplasia has been high. Ticagrelor has also been linked to inhibition of smooth muscle cell proliferation and, hence, reduced intimal hyperplasia.

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Elevated preoperative BNP levels and advanced age together are significant predictors for the development of postoperative AF in patients undergoing isolated CABG with CPB.

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AbstractGlomus caroticum tumors, usually used as an alternative term for carotid body tumor, are of neuroectodermal origin and a part of the extra adrenal neuroendocrine system pathologies. These abnormalities are the most frequently detected paraganglioma in the localization of the head and neck. In our report, we present a giant tumor mass on the left side which was operated on successfully with a review of our experience retrospectively. Between the dates of June 1995 and October 2009, 47 patients, all of which had a glomus caroticum tumor, underwent to surgery. Tumor presented a wide variety of size and clinical presentations.

Objectives. The widespread use of percutaneous coronary intervention (PCI) has resulted in an increasing number of patients who have undergone prior PCI being referred for coronary artery bypass graft grafting (CABG). The aim of this study was to determine the association between previous PCI and early and midterm outcomes after CABG. Methods. A total of 54 patients undergoing elective CABG (group 1) between January 2008 and January 2009 were compared to 46 patients who had a history of bare metal stent implantation before CABG (group 2). Mean follow-up was 12 months. Results. The average time interval to CABG following initial PCI was 18.5 months. There was no significant difference in demographic features and risk factors between the two groups (p>0.05). There were also no significant differences in intraoperative and postoperative data, and no significant differences for in-hospital mortality, cardiac mortality and total mortality and in the number of rehospitalizations for cardiac or for all-cause reasons (p>0.05). Conclusions. In this study, previous PCI did not significantly influence the outcomes of CABG in a 12-month follow-up period.

After cisplatin and bleomycin-containing chemotherapy (CTx) for testicular cancer, part of the patients may develop acute or long-term cardiovascular toxicity. In the present case, we reported that a 58-year-old male patient presenting with testicular tumors who developed acute peripheral arterial disease during combination CTx with bleomycin, etoposide, and cisplatin. Superficial femoral artery occlusion not responded to structure thrombolytic and anticoagulators treatment. Left lower extremity was amputated below knee. In patients with high risk of cardiovascular disease, prophylactic anticoagulation may be recommended. The risk of causing factors of thromboembolism in patients with testicular cancer under cisplatin and bleomycin-containing CTx should be evaluated.