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Ecstasy (3,4‐methylenedioxymethamphetamine or MDMA) is used with increasing frequency as a recreational drug. Accumulated evidence over recent years indicates a growing demand for the drug with a corresponding increase in number of reports of adverse effects from its use. There are reported metabolic disturbances due to MDMA use. These, in addition to the prolonged exercise involved in dancing at ‘raves’ where MDMA may be used, may exacerbate ketoacidosis. We report two cases of ketoacidosis complicated by MDMA ingestion.

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Animals were reared on a diet of commercially available corn grits from weaning to approximately 120 days of age. Littermate controls were fed Purina Laboratory Chow. The subjects' learning ability was tested in a two-way active avoidance task and a black-white visual discrimination task. The grits-fed animals did not develop physically and remained as small as weanling rats throughout the study. The data from the learning tasks indicate that there were no differences in learning ability between the protein-malnourished animals and the normallittermates.