The separation and preconcentration of copper(II), lead(II), and cadmium(II) ions on magnetic graphene oxide (MGO) by solid-phase extraction was carried out. Quantitative recovery was obtained by adsorption of analytes on MGO at pH 6 and elution of 3 M HNO3 in 10% acetone. To optimize the presented method, the effects of various parameters-including pH, eluent conditions, and vortex time-were examined. Matrix effects were also investigated. Mean recoveries of the analytes were between 95 and 105%. The proposed method was validated by applying it to certified reference materials. Addition and recovery tests were also performed. The method was applied to verify the analyte content of several water and food samples.
Background: Bupropion is a new-generation monocyclic antidepressant that has been accidentally found to have potential effects on reducing nicotine addiction. It is structurally similar to stimulants such as amphetamine and inhibits dopamine and noradrenalin reuptake selectively.Case Reports: We report two cases with no history of epilepsy who took oral bupropion for depression and had generalised tonic-clonic type of seizures in their follow-ups. Conclusion:After an overdose of bupropion, clinical effects are seen primarily on the neurological, cardiovascular, and gastrointestinal systems. Neurological effects can include tremor, confusion, agitation, hallucinations, coma, and seizures.
Background/aim: We aim to determine the effects of low-dose atorvastatin treatment together with crush fluid resuscitation on renal functions and muscle enzyme levels in a rat model of crush syndrome. Materials and methods:The study involved female Wistar Albino rats weighing 250-300 g that were housed with free access to food and water. The crush model was obtained by compression. Rats were randomly divided into four groups: control (C) group, atorvastatin + crush fluid (ACF) group, crush fluid (CF) group, and hypertonic saline (%3) + mannitol + sodium bicarbonate (SM) group. Blood was obtained at 24, 48, and 72 h, and serum creatinine kinase, myoglobin, urea, creatinine, and lactate dehydrogenase levels were studied.Results: All parameters were statistically significantly higher in the control group than in the treatment groups at all hours. However, there was no statistically significant difference among treatment groups regarding any of the parameters. Conclusion:This is the first study determining the role of atorvastatin in the treatment of renal ischemia/reperfusion injury in a crush syndrome and rhabdomyolysis model setting. Larger studies with different atorvastatin doses are required to define the role of this drug in the treatment of renal ischemia/reperfusion injury during crush syndrome.
Neuroprotective agents such as methylprednisolone and sildenafil may limit damage after spinal cord injury. We evaluated the effects of methylprednisolone and sildenafil on biochemical and histologic changes after spinal cord injury in a rabbit model. Female New Zealand rabbits (32 rabbits) were allocated to 4 equal groups: laminectomy only (sham control) or laminectomy and spinal trauma with no other treatment (trauma control) or treatment with either methylprednisolone or sildenafil. Gelsolin and caspase-3 levels in cerebrospinal fluid and plasma were determined, and spinal cord histology was evaluated at 24 hours after trauma. There were no differences in mean cerebrospinal fluid or plasma levels of caspase-3 between the groups or within the groups from 0 to 24 hours after injury. From 0 to 24 hours after trauma, mean cerebrospinal fluid gelsolin levels significantly increased in the sildenafil group and decreased in the sham control and the trauma control groups. Mean plasma gelsolin level was significantly higher at 8 and 24 hours after trauma in the sildenafil than other groups. Histologic examination indicated that general structural integrity was better in the methylprednisolone in comparison with the trauma control group. General structural integrity, leptomeninges, white and grey matter hematomas, and necrosis were significantly improved in the sildenafil compared with the trauma control group. Caspase-3 levels in the cerebrospinal fluid and blood were not increased but gelsolin levels were decreased after spinal cord injury in trauma control rabbits. Sildenafil caused an increase in gelsolin levels and may be more effective than methylprednisolone at decreasing secondary damage to the spinal cord.
To evaluate differences between cultivated and wild mushroom poisoning in terms of clinical characteristics, laboratory findings, and complications. we also aimed to determine the differences among patients in regard to presence of complications. Materials and Methods: We evaluated adults who were diagnosed with mushroom poisoning in a 4-year period between 2014 and 2017. The following characteristics of patients were recorded: age, sex, complaints, time until hospital admittance, time until symptom onset, mushroom source, any interventions until patient arrived to the hospital, laboratory findings, complications, length of stay (LoS) at hospital, and patient discharge status. Results: A total of 168 patients were enrolled in the study, of which 111 were poisoned by wild mushrooms and 57 were poisoned by cultivated mushrooms. Cultivated mushrooms were more frequently the cause of poisoning in patients who lived in metropolitan and urban areas. Patients who consumed wild mushrooms had higher troponin levels, lower base excess values and longer LoS at hospital. Conclusion: Studies on MP usually evaluate patients according to mushroom type and onset/severity of complications. We evaluated patients in terms of the source of mushroom (wild/cultivated) and the presence of complications, which is a different approach. We aimed to identify the differences between cultivated and wild MP; however, we ended up finding that these conditions are mostly similar in terms of clinical characteristics, laboratory findings and complications. We also believe that the identification of complications and their severity is an important determinant of their effects on prognosis.
Materials and MethodsAll records for children aged between 0-17 years who were admitted to the Konya Training and Research Hospital, Emergency
1 GirişElektrik enerjisi gelişen dünyamızda vazgeçilmez bir gereksinimdir. Ancak tedbirsizliği ve ihmali ciddi problemlere neden olabilmektedir. Elektrik çarpmaları birden fazla sistemi tutan yaralanmalardır ve mortalite oranları %3-15' dir (1). Elektrik çarpmaları ve onunla ilişkili yaralanmalarına eşlik eden yüksekten düşme ve buna bağlı ek yaralanmalar hastaların mortalite ve morbiditesine etki eder (2). Güçlü elektrik çarpmalarından veya elektrik şok-larından sonra ya da epilepsi nöbetlerinde görülen yaygın kasılmalar sonrası omuz dislokasyonları ortaya çıkabilir (3). Elektrik yaralanmalarında gelişen hasar termal etkiye veya elektriğin doğrudan etkisine bağlıdır. Düşük voltajlı yaralanmalar sıklıkla evde olur, temasın sonlanmaması yüzünden tetani meydana gelebilir ve sıklıkla tehlikeli kardiyak bozukluklar ortaya çıkar. Yüksek voltajlı yaralanmalar sıklıkla iş yerinde meydana gelir. Bu yaralanmalarda temas süresi kısadır, ancak ciddi doku yıkımı ve sekonder hasarlara sebep olur. Yüksek voltaj temasları kardiyak arrest, rabdomiyoliz, kompartman sendromu ve ciddi doku yaralanması ile ilişkilidir. Vücutta en çok etkilenen sistemler; kardiyovasküler sistem, kas-iskelet sistemi, merkezi sinir sistemi, böbrekler ve cilttir. Ciddi yanıklar, miyokard hasarı, merkezi sinir sistemi hasarı ve multiorgan yetmezliğinin derecesi prognozu belirleyen faktörlerdir. OlguOtuzbeş yaşındaki erkek hasta işyerinde yüksek akım-lı sanayi elektriğine maruz kaldıktan sonra acil servise getirildi. Hastanın geldiğinde genel durumu iyi, bilinci açık, oryante, koopere, Glasgow Koma Skalası 15 puan idi. Tansiyon arteriyel:130/76 mmHg, solunum sayısı:18/ dk, nabız:78/dk olarak ölçüldü. Hasta sol kolda güçsüzlük, uyuşma ve hareket kısıtlılığı tarif ediyordu. İnspeksiyonda sol el 2. parmak pulpasında giriş yanığı, sol ayak plantar yüzde yaklaşık 12x3 cm'lik siyah nekroze alan, lateralinde 8 cm çapında bül ve bu bölgede 2x1 cm'lik muhtemel çıkış yanığı mevcuttu (Resim 1,2 Elektrik çarpmaları birden fazla sistemi etkileyen, morbidite ve mortalitesi yüksek olan yaralanmalardır. Elektrik yaralanmalarıyla ilişkili komplikasyonların yanı sıra bu yaralanmalara eşlik eden yüksekten düşme gibi yaralanmalarda önemli bir problemdir. Elektrik çarpması sonucu meydana gelen yaralanmaların değerlendirmesinde cilt yanıklarıyla orantısız olarak ciddi diğer organ yaralanmaları oluşabilmektedir. Elektrik çarpmalarından veya elektrik şoklarından sonra görülen yaygın kasılmalar sonrası omuz dislokasyonları, cilt yanıkları, rabdomiyoliz ve kompartman sendromu gibi derin doku hasarları ortaya çıkabilir. Bu çalışmada yüksek voltajlı elektrik akımına maruziyet sonrası sol elinde cilt yanığı, sol ayakta cilt yanığı ve nekrozu, sol omuz anterior dislokasyonu ile birlikte takiplerinde rabdomiyoliz gelişen bir olguyu sunmayı amaçladık. Anahtar sözcükler: Elektrik çarpması, omuz dislokasyonu, rabdomiyolizAnterior shoulder dislocation and rhabdomyolysis accompanied by high-current electric shockElectric shocks are the injuries with a high morbidity and mortality that affe...
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.