Background and aim: There is evidence to support the favorable impact of physical activity (PA) on brain volume. However, the empirical evidence exploring the relationship between physical and sedentary behavior remains mixed. We aimed to explore the relationship between physical activity and sedentary behavior and brain volume. Methods: The study sample (n = 150, mean age= 39.7 years) included patients interviewed with the International Physical Activity Questionnaire (IPAQ) who underwent an MRI brain scan. From the images obtained, we measured total intracranial, gray matter, and white matter volume along with the hippocampus, amygdala, parahippocampal gyrus, and posterior cingulate gyrus. Multivariable linear regression analysis was done. Results and discussion: Left hippocampus and overall physical activity were positively and significantly associated (β = 0.71, p = 0.021) whereas time spent on vigorous physical activity showed a negative association (β= −0.328, p = 0.049) with left hippocampal volume. Conclusion: We found a positive association between total physical activity and the left hippocampus, whereas vigorous physical activity showed a negative association with the left hippocampus.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.