Aims and Objectives:The aim of the present study was to investigate systemic levels of inflammatory markers of cardiovascular diseases like C-reactive protein and interleukin-6 in patients with chronic periodontitis, in comparison to periodontally healthy individuals.Materials and Methods:A total of 42 individuals, both males and females above the age of 30 years, were included in the study. Healthy controls (Group I, n = 14), chronic localized periodontitis (Group II, n = 14), and chronic generalized periodontitis (Group III, n = 14), all without any medical disorder, were recruited. Peripheral blood samples were taken and C-reactive protein (CRP) levels were estimated in the serum samples by using the Particle-Enhanced Turbidimetric Immunoassay (PETIA) technique. Serum samples of Interleukin-6 (IL-6) were assayed by using the Chemiluminescent Immunoassay (IMMULITE) technique.Results:When mean CRP levels were compared between the groups, group III showed statistical significance when compared to group I (P = 0.04). Group III had a higher median IL-6 level (6.35 pg/mL) than Group II (< 5.0 pg/mL) and group I (< 5.0 pg/mL). Differences in median values of IL-6 were not statistically significant in any group (P = 0.29).Conclusion:Periodontitis results in higher systemic levels of CRP and IL-6. These elevated inflammatory factors may increase inflammatory activity in atherosclerotic lesions and potentially increasing the risk for cardiovascular events.
This study is intended to evaluate the changes in Electrocardiogram (ECG) in apparently healthy adult male smokers. This cross-sectional study covers 40 smokers, who smoked on an average 10 cigarettes per day for at least 5 years, and 40 non-smokers to find out the possible risk factors for cardiovascular disorders. This study was conducted during April 2011 to April 2012 in the Department of Physiology of Andhra Medical College, on subjects whose age ranged from 20 to 60 years. The ECG results were evaluated for different parameters like heart rate, P-wave, P-R interval, QRS complex, QT interval, and T-wave. The results were analyzed using student's t-test. The probability (p value) was calculated. The analysis showed that QRS and QT interval were shortened and that the QTc interval was widened in the smokers, although the values did not show any statistical significance. From the statistical analysis of the results obtained in the present study and their comparison with those of published reports, it appears that smoking 10 cigarettes per day for 5 Years does not cause major change in ECG wave forms.
Introduction: Left ventricular ejection fraction (LVEF) has been used for many years to assess left ventricular systolic function. Over time, patients may have LVEF measurements performed with the use of different imaging modalities.Ejection fraction measurements obtained with both the Teichholz and Simpson's methods are directly comparable for evaluation of ejection fraction.This study is done to compare Teichholz method to simpson's method in patients with global hypokinesia of left ventricle. Methods: Prospective cross sectional study was done in 150 patients who underwent echocardiography at Chettinad Super Speciality hospital. Using conventional 2D echocardiography and Doppler Echocardiography left ventricular ejection fraction was assessed in various views (Apical four chamber, Apical two chambers and parasternal long axis) using VIVID S5 and Esaote.From the total subjects, 105 patients were male and 45 were females. In this study, we compare Teichholz method to Simpson's method in patients with global hypokinesia of left ventricle. Results: Out 150
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