Effective removal of drilling-mud filter cake during well completion is essential to reduce the formation damage caused by drilling activities in many production and injection wells. This task is very difficult to achieve, especially in horizontal/multilateral wells. Harsh chemical treatments (acids, oxidizers, and chelating agents) have been used extensively to conduct water-based mudcake cleanup treatments. However, these approaches have been limited due to the associated high corrosion rates and un-even mudcake removal. With their controlled reaction with the mudcake, mild chemical nature, better health, safety and environmental (HSE) profile, enzymes provide an excellent alternative to harsh chemical treatments in high temperature formations. However, their use has been limited to relatively low temperature applications due to their instability at elevated temperature values.In this work, two enzymatic systems were evaluated: old α-amylase system and new structurally reinforced α-Helix system. The old enzyme was found to form a potentially damaging precipitate at reservoir temperature above 100 o C. The degree of this damage was assessed using size-matching technique and core-flood experiments. This potential of secondary formation damage was drastically reduced in the new improved enzyme system. Enzyme denaturing was minimized by protecting the catalytic center using preferential hydration of proteins with a Polyol.The effectiveness of the new system was proven in the lab through comparative tests. Bioassay by reducing sugar estimation showed better biopolymer hydrolyzing capability of the new system at higher temperatures. In contrast to old enzyme system, core-flood experiments, conducted at high temperatures, using new enzyme system, showed the enzyme denaturing did not occur and the core oil permeability increased at stabilized pressure. In addition, this paper will also highlight the advantages and disadvantages of each enzyme system in terms of stability, compatibility, and mudcake damage reversal.

Hydraulic fracturing is a widely used technology to enhance the productivity of low-permeability reservoirs. Fracturing fluids using guar as the rheology builder leaves aside residual polymer layers over the fractured surface, resulting in a restricted matrix to fracture flow, causing reduced well productivity and injectivity. This research developed a specialized enzyme breaker and evaluated its efficiency in breaking linear and cross-linked guar-polymer gel as a function of time, temperature, and breaker concentration targeting a high-temperature carbonate reservoir. The study began with developing a high-temperature stable galacto-mannanase enzyme using the "protein-engineering" approach, followed by the optimization of fracturing fluids and breaker concentrations measuring their rheological properties. The thermal stability of the enzyme breaker vis-a-vis viscosity reduction and the degradation pattern of the linear and cross-linked gel observed from the break tests showed that the enzyme is stable and active up to 120 °C and can reduce viscosity by more than 99%. Further studies conducted using a high-temperature high-pressure HT-HP filter press for the visual inspection of polymer cake quality, filtration loss rates, and cake dissolution efficiency showed that a 6 h enzyme treatment degrades the filter cake by 94−98% compared to 60−70% degradation in 72 h of the natural degradation process. Coreflooding studies, under simulated reservoir conditions, showed the severity of postfracture damage (up to 99%), which could be restored up to 95% on enzyme treatment depending on the treatment protocol and the type of fracturing gel used.

Significant formation damage can occur during drilling operations because of the invasion of drilling fluid fines and filtrates that lead to pore blocking and saturation alteration mechanisms. This study demonstrates the ways to minimize drilling fluid-related damage and the removal of the deposited filter cake in the carbonate reservoir through judicious selection of bridging particles using “ideal packing theory” and formulation of an enzyme-based clean-up fluid with an acid precursor. The polymer-based drill-in-fluid with a mixed grade of CaCO 3 bridging particles resulted in a compact filter cake with reduced filtration loss preventing internal pore damage significantly. Several ester hydrolysis reaction kinetics were studied, and finally, one combination was chosen as the suitable acid precursor because of its ability to generate a required concentration of acid within the downhole condition. The return permeability of mud-damaged carbonate core plugs was higher than 95% after exposure to the clean-up solution. The corrosion rates were found to be significantly below the industry limits, and the use of acid corrosion inhibitors is eliminated.

Hydraulic fracturing, commonly referred to as fracking, is a widely used technology to enhance the productivity of low-perm reservoirs and the aqueous-based fracturing fluids use guar as the rheology builder. Residual polymer layer over the fractured surface results in a reduced matrix to fracture permeability, causing reduced well productivity. This research aims to develop a specialized mannanase enzyme and evaluate its efficiency in degrading linear and cross-linked guar polymer gel as a function of time, temperature, and breaker concentration, to enhance the effectiveness of the fracturing process and yielding higher production. The study begins with developing high-temperature stable mannanase using "protein engineering" tools to minimize denaturation at high temperatures and the underlying formation chemistry, followed by optimization of polymer, crosslinker, and breaker concentration through the measurement of rheological properties at moderate to high temperature. Initial studies were conducted using HT-HP filter press and filter papers as porous media for visual inspection of polymer cake dissolution efficiency. Final conclusions were drawn from the simulated coreflooding studies, wherein the injection and production return permeabilities were investigated on post-fracture and enzyme-treated cores, where the breaker was mixed with the frac fluid applied once the frac fluid is in place. The thermal stability of the enzyme breaker vis-à-vis viscosity reduction and degradation pattern of linear and cross-linked gel observed from the break test showed that the enzyme is stable up to 250 °F and can reduce viscosity by more than 1800 cp (99% breaking ability).

Horizontal wells enable drainage from a longer wellbore which helps to allow lower drawdown rate compared to vertical wells, minimizing gas or water coning. However productivity can be seriously affected unless mud cake damage is efficiently removed from all producing intervals along the horizontal wellbore. In recent years eco-friendly and non-corrosive bioenzymes (α/β-amylase) have shown great potential in cleaning wellbores uniformly and achieving higher well productivity. However in a low pressure fractured reservoir, there is always a possibility of localized reaction and loss of the clean-up fluid, unless the reactivity of the fluid is engineered based on the given well parameters. In this study α-amylase enzyme is modified to withstand higher thermal shock by structurally reinforcing the β-Helix layer to strengthen the catalytic centre by preferential protein hydration technique. Buffering was done to maintain different system pH and kinetic rate constant is derived through reducing sugar release measurement by DNS method using starch-xanthan gum-CaCO3 based drill-in-fluid as substrate. Though the overall reaction is extremely complex, a good correlation could be drawn between system pH and the rate of breaking mud cake into simple sugar. The kinetic rate constant index is used in final formulation of enzymatic clean up fluid for application in high temperature (110 °C) long horizontal wells drilled in carbonate formation, which allowed different soaking time due to operational constraints. The results show that there is excellent correlation between laboratory prediction and clean up efficiency in terms of well productivity.The study showed that each individual well demands a specific formula for clean-up fluid and higher than prognosed production could be achieved through custom formulation, based on well condition and operational requirement.