The present method is simple, rapid, and most efficient green protocol for the synthesis of 2-amino-4H-pyran derivatives using highly inexpensive and easily available DABCO as an efficient catalyst under grinding and solvent free condition at room temperature.
The present work describes an efficient, green, and direct approach for the synthesis of amido alkyl naphthols via one-pot multicomponent solvent-free reaction (MCR) of substituted aromatic aldehydes, β-naphthols and urea by the use of easily available, non-toxic and cost-effective Lewis acid catalyst magnesium sulphate (MgSO4.7H2O). The important characteristics of this reaction are eco-friendly and mild reaction conditions, excellent yield of the products, shorter reaction time, economically cheaper and environmentally friendly catalyst MgSO4.7H2O. Also, clean reaction, non-column purification and operational simplicity are some of the additional significant features of this approach.
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