The HYDROVIEW® intraocular lens is a biconvex foldable hydrogel lens configured as a conventional one-piece design. The unfolding time is approximately constant with lens dioptric power at an average of2.4 seconds, and increases with the length oftime the lens is held in air prior to implantation. Mechanical recovery can be modeled as a non-linear critically damped harmonic oscillator, which demonstrates the controlled manner ofunfolding. The Modulation Transfer Function at 30 cycles/degree reaches an average of 95% of its pre.-fold value within one hour after being released from folding and recovers completely to its pre-fold values within 24 hours. Interferometrically measured root-mean-square transmitted wavefront error and Strehl Ratio both recover to pre-fold values within 24 hours after folding. Dehydration for a period of 10 minutes followed by folding, then rehydration and unfolding was found to have no significant effect on lens power (<0. 15 Diopter) or resolution. Neither temperatures in excess of 120°C, which may be used during sterilization, nor temperatures as low as -85°C were found to have any significant effect on lens power and resolution.
Aus Exalton (I) entsteht nach vorangegangener Lithiierung mit Phenylselenbromid über (II) bei anschließender Oxidation und Selenoxid‐β‐Eliminierung die Verbindung (III), die zu (i)‐Muscon (IV) methyliert wird.
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