Tetanus is a potentially fatal disease of the nervous system arising from toxins produced by Clostridium tetani, an anaerobic bacterium found in soil [1]. Characterized by muscular rigidity, spasms and autonomic dysregulation its identification and, importantly, its prevention remain critical to the welfare of at risk patients. We present the case of a twenty two year old woman who presented to hospital with trismus and generalized muscle spasms three days following a dog bite to the right hand. Here, we discuss the presentation of generalized tetanus and the use of neurophysiology to facilitate its diagnosis.
This audit aims to assess the rates of baseline nucleic acid amplification testing (NAAT) for chlamydia and gonorrhoea infection and serum syphilis testing among newly attending HIVinfected persons at the HIV clinic of St James's Hospital, Dublin.
Antimicrobial associated encephalopathy (AAE) is a well-documented, though under recognised, adverse event associated with antimicrobial use.1 Clinical manifestations of AAE are varied, ranging from myoclonus and seizure to an encephalopathy with cerebellar signs.1 The phenotypic presentation of the encephalopathy syndrome is, in general, governed by the antimicrobial in question. Given its apparent rarity in everyday clinical practice, awareness of AAE is crucial for physicians. We describe a reversible encephalopathy characterised by confusion, myoclonus and stupor in a 76 year old gentleman on antimicrobial therapy for a peri-rectal abscess.
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