In his seminal paper on the urban land market, Alonso notes that when a purchaser acquires land, he acquires two goods (land and location) in one transaction, and a single payment is made for the combination. Thus it is possible to trade off a quantity of land against location, the principle underlying Alonso's bid-rent analysis. It is argued that the Alonso model of bid-rent analysis is still applicable to those types of economic activity which display a hierarchy of use in terms of distance from the city centre. The concern here is with hotel location, and we develop a model of the Alonso type which casts light upon the intraurban location decisions of hotels.
Autophagy-related (ATG) proteins regulate autophagy, but recent work indicates that some also have autophagy-independent roles. Here, Mauthe et al. perform an unbiased siRNA screen to examine the effects of ATG protein depletion on viral replication and demonstrate autophagy-independent functions for ATG13 and FIP200 in the picornaviral life cycle.
This paper proposes a monitoring framework to be used during the planning stage for a sports mega-event. The research identifies a lack of monitoring and evaluation studies during the development stage for sports mega-events. Importantly, it notes the absence of research which evaluates an event systematically from the outset of the process and from the perspectives of host residents and event planners. The framework was developed on the basis of the philosophical approach of pragmatism; it focused on a sustainable development perspective, and it was applied to a case study of the Kaohsiung 2009 World Games. A survey of the views of 606 host residents about the potential impacts of the event revealed that the respondents tended to show higher levels of agreement on the host benefits. The results of 38 interviews with various stakeholders indicated big gaps in both the city's long-term development aspirations and the Games themselves and also in the event strategies adopted. Using this information, key sustainability issues can be identified and monitored during the event planning stage so that the desirable outcomes of events can be enhanced and then sustained in the longer term.
In a simulated crime situation, 3 groups of eyewitnesses viewed 2 target persons through a one-way mirror and were tested for accuracy of identification after delay periods of 2, 21, or 56 days. Subjects made identifications from either a live "show-up" or by looking at photographs. In both methods of testing only 1 of the 2 targets was actually present in the 5-man array. Results indicated that delay affects number of false alarms, test method affects number of hits. Photographs produced less accurate performance than live show-up. More than 60% of the subjects erroneously selected one of the 4 distractor persons, a finding relevant to the use of eyewitness identification in criminal investigations. Only 28% of the subjects made no errors of identification.
How has the Antarctic Ice Sheet responded to or influenced global climate change? This simple question has been difficult to address because the long‐term records of the ice sheet's fluctuations are poorly constrained with geologic data from Antarctica. Thus studies to date have not convincingly established how specific Antarctic Ice Sheet events correlate with climatic, eustatic, or other phenomena known from low‐latitude and deep‐sea records. This study focused on documenting the direct record of ice sheet advance and retreat to the Antarctic Peninsula's shelf edge. On the peninsula's outer shelf, seismic reflectors interpreted to be subglacial unconformities were correlated with published results from Ocean Drilling Program Leg 178. Lithologic and chronologic control at two drill sites provided ground truth for the seismic interpretation and the timing of the Antarctic Peninsula Ice Sheet grounding events. This synthesis showed that grounded ice advanced to the shelf edge on at least 12 occasions between 5.12 and 7.94 Ma.
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