The potential prebiotic properties of Panax ginseng polysaccharides were studied using ten strains of Lactobacillus plantarum isolated from traditional Chinese fermented foods. These probiotics showed different growth characteristics depending on the extract and strain specificity. L. plantarum C88 showed higher cell densities and growth rate when cultured on P. ginseng polysaccharides. In the in vitro antioxidant assay, P. ginseng polysaccharides combined with L. plantarum C88 were found to possess significant DPPH, ABTS and superoxide anion radicals scavenging activities, and acidic polysaccharides showed better antioxidant activity than neutral polysaccharides. Furthermore, we evaluated the antioxidant effect of acidic P. ginseng polysaccharide combined with L. plantarum C88 strain in natural ageing mice in vivo. Acidic P. ginseng polysaccharide and L. plantarum C88 together inhibited the formation of malondialdehyde (MDA) and increased the activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), catalase (CAT) and total antioxidant capacities (T-AOC) in a dose-dependent manner.
To cite: Ping et al. Can acupuncture improve sleep quality and anxiety among women during perimenopause?A protocol for systemic review and metaanalysis. Inplasy protocol 2021120012.
Review question / Objective: This systematic review protocol aims to provide the methods used to evaluate the effectiveness and safety of abdominal acupuncture therapy for treating insomnia. Condition being studied: Insomnia is a subjective symptom of poor sleep quality and low sleep duration due to personal reasons such as inability to fall asleep or easy to wake up and difficulty in falling asleep, Acupuncture is a treatment that promotes health by inserting needles into specific acupoints on the human body at an appropriate depth. Acupuncture treatment of insomnia has the characteristics of simple operation, non-toxic side effects, positive curative effect, and high safety. Abdominal acupuncture is an unusual acupuncture therapy that treats systemic disorders by acupuncturing the viscera and meridians in the abdomen; Western medicine believes that it is the brain-gut axis, which is the theoretical basis of abdominal acupuncture for the treatment of insomnia. The brain-gut axis refers to a bidirectional regulatory system of interactions between the gastrointestinal tract and the brain.abdominal acupuncture stimulates the abdominal tract and improves sleep quality by regulating the secretion of sleep-related brain-gut peptide content through the brain-gut axis. INPLASY registration number: This protocol was registered with the International Platform of Registered Systematic Review and Meta-Analysis Protocols (INPLASY) on 23 October 2021 and was last updated on 23 October 2021 (registration number INPLASY2021100088).
Background: Insomnia is characterized by high incidence, easy recurrence, and difficulty in curing. Serious insomnia not only seriously affects the body organ function, but psychological patients also cause great damage. Abdominal acupuncture (AA) has fewer side effects and is increasingly used to treat insomnia. This study aimed to systematically review the effectiveness and safety of abdominal acupuncture in the treatment of insomnia.Methods: Literature on abdominal acupuncture for insomnia in the PubMed, Excerpt Medica Database(Embase), Cochrane Central Register of Controlled Trials, Web of Science, China National Knowledge Infrastructure Database, China Biomedical Literature Database, Chinese Scientific Journal Database, and Wan Fang databases were searched from the creation of these databases to October 3, 2021. In addition, the reference lists of studies meeting the inclusion criteria will also be searched to achieve a comprehensive retrieval of the maximum. All randomized controlled trials of AA for treating insomnia were included. Two reviewers will conduct literature screening, data extraction, and quality evaluation respectively. The main outcome was the Pittsburgh Sleep Quality Index, and the secondary outcomes included clinical efficacy and safety. RevMan 5.4.1 software was used for mate analysis.Results: This study aimed to evaluate the current status of AA treatment for insomnia, with the aim of illustrating the effectiveness and safety of abdominal acupuncture.Conclusion: This study will provide high-quality evidence to evaluate the effectiveness and safety of AA in treating insomnia.
Background: Insomnia is characterized by high incidence, easy recurrence, and difficulty in curing. Serious insomnia not only seriously affects the body organ function but also causes great damage psychological. Umbilical acupuncture (UA) has fewer side effects and is increasingly used to treat insomnia. This study aimed to systematically review the effectiveness and safety of UA in the treatment of insomnia. Methods: Literature on UA for insomnia in PubMed, Excerpt Medica Database, the Cochrane Central Register of Controlled Trials, Web of Science, China National Knowledge Infrastructure Database, China Biomedical Literature Database, Chinese Scientific Journal Database, and Wan Fang Database were searched from the creation of these databases to October 3, 2021. In addition, the reference lists of studies meeting the inclusion criteria will also be searched to achieve a comprehensive retrieval of the maximum. All randomized controlled trials of UA for treating insomnia were included. Two reviewers will conduct literature screening, data extraction, and quality evaluation respectively. The main outcome was the Pittsburgh Sleep Quality Index, and the secondary outcomes included clinical efficacy, and safety. RevMan 5.4.1 software was used for mate analysis. Results: This study aimed to evaluate the current status of UA treatment for insomnia, with the aim of illustrating the effectiveness and safety of UA. Conclusion: This study will provides a high-quality evidence to evaluate the effectiveness and safety of UA in treating insomnia. Registration: PROSPERO CRD42021283036.
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