As alterações no hemograma estão direta ou indiretamente relacionadas com câncer e são pouco descritas em cadelas com neoplasia mamária. O objetivo deste estudo foi analisar as alterações hematológicas em 161 cadelas portadoras de neoplasia mamária e correlacionar à progressão da doença. As principais alterações hematológicas encontradas foram anemia normocítica e normocrômica e leucocitose neutrofílica, sendo ambas mais frequentes em cadelas em estádio avançado (III, IV ou V) da doença.Conclui-se que as alterações laboratoriais de anemia e leucocitose verificadas em cadelas com neoplasia mamária estão correlacionadas positivamente com o estádio avançado da doença.

Brazilian Spotted Fever (BSF) is a lethal rickettsiosis in humans caused by the bacteria Rickettsia rickettsii, and is endemic in some areas of Brazil. Horses and dogs are part of the disease's life cycle and they may also serve as sentinel animals in epidemiological studies. The first human BSF case in the State of Paraná was reported in 2005. The present study was conducted in the municipality of Almirante Tamandaré, where no previous case of BSF was reported. Serum samples were collected from 71 horses and 20 dogs from nine properties in the area. Ticks were also collected from these animals. All farmers completed a questionnaire about their knowledge of BSF and animal health management. Serum samples were analyzed by indirect immunofluorescent-antibody assay (IFA) using R. rickettsii and R. parkeri as antigens. Ticks were analyzed by PCR for Rickettsia sp., and all of them were PCR-negative. Six horses (8.45%) and 4 dogs (20%) were identified as seropositive. Farmers were not aware of the correlation between the presence of ticks and risk of BSF. Although a non-endemic area, Almirante Tamandaré is a vulnerable environment for BSF and effective tick control measures are required.

RESUMO As proteínas de fase aguda (PFA) apresentam concentrações séricas alteradas mediante processos infecciosos, ABSTRACT Acute phase proteins (APPs) are serum proteins whose concentrations change after infectious and infl ammatory disease, and cancer. The aims of this study were to evaluate changes in APPs concentration and to correlate these fi ndings with histological classifi cation and WBC in female dogs with mammary tumors. APPs were studied in 45 female dogs with mammary tumor distributed in the following groups: benign (n=13), malignant without tumor ulceration (n=24), and malignant with tumor ulceration (n=8). SDS-polyacrylamide gel (SDS-PAGE) electrophoresis was used to measure APPs concentrations (albumin, ceruloplasmin, transferrin, haptoglobinHp,

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IntroductionPerineal hernia (PH) occurs due to the weakness and separation of the pelvic diaphragm, resulting in the protrusion of pelvic or abdominal viscera into the perineal region. The cause of pelvis diaphragm weakening may be multifactorial, and it is believed to be associated with hormonal imbalance, prostatic enlargement, straining, and congenital or acquired muscle weakness or atrophy (1). PH is frequently observed in middle-aged male dogs that are sexually intact (2,3).Surgical reconstruction of the pelvic diaphragm is commonly recommended for the correction of PH. Several surgeries have been suggested, including a simple appositional technique, vascularized muscle flap transposition (internal obturator muscle, superficial gluteal muscle, semitendinosus muscle), and the use of implants or graft techniques (synthetic mesh, porcine small intestinal submucosa, canine small intestinal submucosa, autologous tunica vaginalis) (4-10). A laparotomy for colopexy and/or cystopexy may be required in complicated PH, in combination with any technique of perineal herniorrhaphy (11). Orchiectomy is recommended at the time of PH repair in intact dogs (12). Complications after PH repair are common and may include recurrence of PH, surgical wound dehiscence and infection, tenesmus, fecal incontinence, and rectal prolapse (2,3). The use of fascia lata grafts has been described to repair PH in a few dogs, with the potential to improve longterm recurrence compared with other techniques (13,14). Based on the successful use of a fascia lata graft, our study hypothesized that a fascia lata flap (FLP) can adequately be transposed to the pelvic diaphragm, achieving long-term support of the ventral and lateral aspects of the PH. The aim of this study was to describe this modified technique for PH repair in dogs. Materials and methods Inclusion criteriaA prospective cross-sectional clinical study was conducted in a veterinary teaching hospital in Brazil. Dogs with PH confirmed by physical exam and perineal ultrasonography were considered for the study. Patients with PH recurrence or with a rectum, prostate, and/or bladder identified in the perineal area were included in the present study.Presurgical evaluation included clinical signs, previous treatment for PH, a complete physical examination, abdominal and perineal ultrasonography, blood cell count, and hepatic and renal serum chemistry profile. AnesthesiaAnesthesia and pain management protocols were similar for all dogs. Dogs were premedicated with morphine (0.4 mg/kg, intramuscularly [IM]) or methadone (0.4 mg/

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Imaging exams are frequently requested during assessment of oncological patients. Although advanced imaging techniques are already available in veterinary medicine, radiographic and ultrasonographic exams remain the basic diagnostic tools in veterinary oncology. This review describes some considerations to improve clinical approach to animals with neoplastic lesions based on the use of radiographic and ultrasonographic exams. The role of these modalities in screening, diagnosis, staging, treatment choice, and follow-up of cancers is discussed. Additionally, a workflow for some type of tumors is described, such as mediastinal lymphoma in cats, as well as mast cell tumors and osteosarcoma in dogs. Situations that require other techniques are also discussed.

Intraoperative ultrasonography (IOUS) is used in medicine for diagnosis and guidance during oncologic surgery. The aims of this study were to assess the performance, feasibility, advantages and difficulties of the IOUS technique in dogs with suspected intra-abdominal tumors. The study included nine client-owed dogs that had suspected intra-abdominal tumors (spleen, liver or bowel) based on transabdominal ultrasound examination and that were subsequently referred for exploratory laparotomy surgery. During surgery, IOUS was performed; results of preoperative transabdominal ultrasonography, inspection by the surgeon and IOUS were compared on a case-by-case basis. IOUS was helpful in determining lesion resection in all cases. Lesions detected solely by the use of IOUS were observed in seven out of nine cases. Analysis of these cases demonstrated that IOUS can be a tool to assist during oncology surgery on the liver, spleen or bowel. Dogs with hepatic tumors can have small non-palpable intraparenchymal nodules, which may be visible by IOUS.