Since low pH affects a relatively broad-spectrum of bacteria and does not act in a mechanism-specific manner, as do antibiotics, antibiotic-resistant strains of bacteria are unlikely to resist the ORC pH effect. Results of this in vitro assessment support the hypothesis that the antimicrobial activity of ORC is effective against antibiotic-resistant microorganisms.

These data support the conclusion that coated polyglactin 910 suture with triclosan provides antimicrobial effect sufficient to prevent in vitro colonization by S. aureus and S. epidermidis.

The results of these in vitro experiments supported the hypothesis that octylcyanoacrylate tissue adhesive is an effective barrier to microbial penetration by gram-positive and gram-negative motile and nonmotile species.

These data support the conclusion that coated polyglactin 910 suture with triclosan provides antimicrobial effect sufficient to prevent in vitro colonization by S. aureus and S. epidermidis.

The data from this in vitro study support the hypothesis that polyurethane foam with chlorhexidine gluconate has an antimicrobial effect against antibiotic-resistant Staphylococcus and Enterococcus species, as well as Candida species.