On-site sanitation is generally advocated as a means to eradicate the health hazards associated with open defecation. While this has provided a welcome upgrade to the livelihoods of millions of people in low-income countries, improved sanitation facilities are increasingly becoming a threat to domestic groundwater-based supplies. Within this context, a survey of pit latrines, domestic wells and improved water sources was carried out in a large rural village of southern Mali. All households were surveyed for water, sanitation and hygiene habits. Domestic wells and improved water sources were georeferenced and sampled for water quality (pH, electric conductivity, temperature, turbidity, total dissolved solids, thermotolerant coliforms, chloride and nitrate) and groundwater level, while all latrines were inspected and georeferenced. A GIS database was then used to evaluate the proportion of water points within the influence area of latrines, as well as to underpin multiple regression models to establish the determinants for fecal contamination in drinking supplies. Moreover, an appraisal of domestic water treatment practices was carried out. This revealed that nearly two-thirds of the population uses bleach to purify drinking supplies, but also that domestic-scale treatment as currently implemented by the population is far from effective. It is thus concluded that existing habits could be enhanced as a means to make water supplies safer. Furthermore, population, well and latrine density were all identified as statistically significant predictors for fecal pollution at different spatial scales. These findings are policy-relevant in the context of groundwater-dependent human settlements, since many countries in the developing world currently pursue the objective of eliminating open defecation.
Tissue engineering's inherent purpose is to develop skin and organ substitutes to sustain, restore or enhance wounded or sick skin functions in vivo. The cutaneous organ tissue makes up the largest organ extension within the human body, and it is also the most outward organ, which makes it the most prone to injury. Due to these problems, constant effort and research has been made looking to solve them. The review's focus is to present recent methods through which tissue engineering, using biocompatible compounds, has achieved a successful cutaneous organ healing. This will include the review of tissue engineering methods such as 3D printing and the usage of a polymeric scaffold, wound dressings and stem cells.
While access to water remains an issue in arid and semiarid regions across the world, aquifers have the potential to help millions of people out of poverty by providing a reliable source of drinking and irrigation water. Manual boreholes are increasingly advocated as a safe and cost-effective substitute to mechanized drilling, as well as to traditional excavation methods. This research banks on the assumption that field and remote sensing data can be integrated within a geospatial database in order to map the viability of manual boreholes based on factors such as rock type, water table depth, landforms, or water quality. The approach presents three main novelties in relation to methodological precedents: (1) outcomes are not only expressed in terms of technical feasibility, but also as a function of drilling time and cost; (2) maps refer to a specific drilling technique; and (3) results take into account borehole diameter, as this constrains both drilling time and cost. The method provides univocal outcomes that can be immediately useful for non-experts, donors, planners, or practitioners and that can be readily exported to other catchment-scale settings. Results were validated against geophysical data.
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