A great challenge to the therapy of ischemic stroke is the poor physicochemical properties and inability of the drug to cross the blood–brain barrier (BBB).
A 1,3-bis[(3,3-dimethylindolin-2-ylidene)methyl]squaraine (ISQ) dye sensitized ZnO nanocomposites via two di®erent preparation methods including hydrothermal and ultrasonic sensitization processes are discussed in this paper. The as-prepared composites were characterized by the X-ray di®raction (XRD), UV-Vis di®use re°ectance spectroscopy (DRS), Raman spectroscopy, and transmission electron microscopy (TEM). Based on the XRD patterns and TEM images, the ISQ/ ZnO nanocomposites still kept the characteristic peaks and the basic morphology of ZnO and ISQ dye. The photocatalytic activity of ISQ/ZnO nanocomposites was investigated by degrading methylene blue (MB) under visible-light illumination. Compared with the MB self-degradation rate, the photocatalytic activity of the ISQ/ZnO composites was enhanced remarkably. The ISQ/ZnO nanocomposites fabricated by ultrasonic sensitization method exhibited excellent photocatalytic degradation rate, approximately 20% higher than that of the hydrothermal sensitization one.
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