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To investigate the effects of meniscectomy on degenerative osteoarthritis, a three-dimensional (3D) finite element (FE) model of the human lower limb is constructed from a combination of magnetic resonance (MR) images and computed tomographic (CT) images that can provide anatomically suitable boundary conditions for a knee joint. Four cases, i.e., the intact meniscus, and the partial, sub-total, and total meniscectomy of the medial meniscus are modeled and simulated. We consider that the cartilage-to-cartilage contact area and the peak contact pressure in the meniscus may be significant parameters in evaluating degenerative osteoarthritis. Partial meniscectomy can be regarded as a better treatment than sub-total/total meniscectomy, and a high possibility of degenerative osteoarthritis is anticipated after total meniscectomy. Moreover, medial meniscectomy has the potential to bring about degenerative osteoarthritis in both the medial compartment and the lateral compartment of a knee joint.

Thirty-three linear measurements and two ratios were derived from 102 12th thoracic vertebrae of the Digital Korean database at the Catholic Institute for Applied Anatomy. Of 35 linear traits, 23 were sexually dimorphic. We created 23 discriminant function equations that predicted sex with 62.7-85.3% accuracy. The analysis using combinations of two factors gave higher accuracies: most equations with accuracies over 80% included at least one measurement involving the coronal diameter of the vertebral endplate. Using stepwise method of discriminant function analysis, three variables predicted sex with 90.0% accuracy: the coronal diameter of the superior endplate of the vertebral body, the ratio of anterior to middle height of the body, and the length of the left mammillary process and pedicle. Coronal dimensions of the vertebral body represented the major sex difference. These equations will help forensic discrimination of the sex of this vertebra among Koreans.

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Unicondylar knee arthroplasty (UKA) has gained popularity in the recent years for treating medial compartment osteoarthritis of the knee joint in the Asian population. There is little information about the anthropometry of the resected bony surfaces of the knee joint in these population groups for designing the appropriate size-matched UKA components. We studied the anthropometry of the resected medial tibial condyles in 50 male and 50 female Korean cadavers by using three-dimensional computer tomography. We measured the anteroposterior dimension, the mediolateral dimension at defined points and the condylar aspect ratio. These measurements were compared with similar dimensions of the tibial components from five conventionally used UKA designs. Statistical analysis was performed using Student's t-test, Paired t-test and Pearson's correlation coefficient. We found that three of the tibial component designs showed mediolateral overhang for the whole range of measured anteroposterior dimensions of the resected medial tibial condyles, whereas one of the designs (DePuy) showed mediolateral undersizing for the smaller AP dimensions and overhang for the larger AP dimensions of the resected medial tibial condyles. Another design (Smith and Nephew) showed mediolateral undersizing for the whole range of measured anteroposterior dimensions of the resected medial tibial condyle. We found a decrease in the condylar aspect ratio with increasing AP dimension for our cadaver population data. However, the majority of the conventional tibial prosthesis showed either a constant condylar aspect ratio or an increasing aspect ratio (DePuy) with the increasing AP dimension of the resected medial tibial condyle. Our study may provide guidelines for designing appropriate tibial UKA components for a majority of Asian sub-populations and encourage similar studies in other population groups.

Therapeutic study, Level I.

The purpose of this study was to develop age-predicting equations from the anterior cortex of the femur of Korean adults. Seventy-two femoral samples (44 male and 28 female) were obtained from Korean cadavers and used to develop the equations. The thin sections (<100-microm thick) were prepared by manual grinding; the sections were not decalcified and were stained with Villanueva bone stain reagent. Analysis of covariance showed no significant differences in age-adjusted histomorphological variables between sexes. In stepwise regression analysis, osteon population density, average osteon area, and the most anterior cortical width were selected for an age-predicting equation which produced a high regression correlation (R(2) = 0.789). The average Haversian canal area was not significantly related to age for any specimen.

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