Background:Men with premature androgenetic alopecia (AGA) are found to be susceptible to cardiovascular diseases, metabolic syndrome (MS), diabetes mellitus and hypertension, and also premature baldness can have a definite negative impact on self-image and self-esteem in these patients. The aim of this study was to assess the strength of association between MS and/or insulin resistance (IR) in males with early-onset AGA.Methods:A total of 50 male patients with premature AGA and equal number of age-matched controls were enrolled in the study. Anthropometric measures, blood pressure, fasting glucose, fasting insulin, high-density lipoprotein cholesterol, and triglycerides were measured for all the participants. Association of IR and MS was evaluated.Results:Most common grade of hair loss was Grade IIIa (32%) of Hamilton–Norwood Scale of hair loss. Five out of 50 cases (10%) and 2 out of 50 controls (4%) had shown association with IR and the difference between the groups was statistically insignificant (P=0.23). Fifteen out of 50 cases (30%) and 4 out of 50 controls had shown association with MS and the difference between the groups was statistically significant (P=0.005).Conclusion:Male patients with early-onset AGA were not associated with IR. MS was associated with male patients with early-onset AGA. The results observed in our study may raise awareness in susceptible individuals that lifestyle changes in early life can reduce the risk of coronary heart diseases in the long term.
Pilomatricoma, is an appendageal tumour of the skin usually seen in head and neck area. They are usually solitary, derived from the ectoderm and arise from the outer root sheath cells of the hair follicle. Multiple pilomatricomas are rare. We present a case of multiple pilomatricomas over the arm of a 13 year old girl.
Introduction: Alopecia areata (AA) is common cause of non-cicatricial alopecia, characterised by single or multiple patches of hair loss affecting scalp and body hair. It is an autoimmune disorder with an unpredictable course and has profound psychosocial impact on the patients. Objective: To study the clinicoepidemiologial profile, precipitating factors and factors influencing the severity of alopecia areata.
Methods and selection criteria:A cross-sectional study was carried out in Dermatology Outpatient Department in a tertiary care hospital from October 2011 to September 2013. All new cases of alopecia areata, aged between 1 and 60 years who presented to the Dermatology OPD and fulfilled the inclusion and exclusion criteria were included. A detailed history was taken and clinical examination conducted and recorded. Descriptive statistics and Chi-Square Test were used. Analyses of these data were done by SPSS software, version 16.0. Results: Majority of the patients belonged to the age group of 21 to 30 years. Psychological stress was the most common precipitating factor with 33 (22.75%). Severity wise, moderate AA constituted 84 (57.9%) patients, mild cases constituted 49 (33.8%) patients, 9 (6.2%) patients presented with ophiasis and severe AA which comprises of alopecia totalis and universalis was found in 3 (2.1%) patients.
Conclusion:We found that psychological stress plays a major role in precipitating AA and influences its severity. Atopic individuals are more likely to develop AA, specifically the ophiasis type. Ophiasis was more often associated with atopy. Other autoimmune diseases like diabetes mellitus and vitiligo are the common associations
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