A Contribution to the Question o/ImTending Postoperative Thrombosis and Embolism~ummary. In the introduction reasons for the assumption are discussed that studies of blood coagulation following chest surgery offer the possibility of gaining clues about the danger of postoperative thromboembolism. Studies were performed on a total of 50 patients; 40 of whom underwent thoracic procedures (cardiac surgery under normal anesthesia, in hypothermia, and in extraeorporeal circulation as well as pulmonary resections), the remaining 10 different operations outside of the thorax served as controls. The scale of the physiologic studies of the blood clotting covered the determination of the factors II, V, VII, VIII and X, the thrombinetime, the antithrombine, the fibrinolysis, the thrombelastogram and the platelet count. The clotting analysis was done daily during the first 8 postoperative days, alternating during the second week and twice during the third week. The following main results were obtained: t. Aa initial drop in activity of the factors II, V, VII and X, a strong increase in activity of the factor VIII, in the thrombelastogram a shortening in the reaction-and the clotting time, an increase in the maximal thrombelasticity, furthermore an increase of the platelet count and a decrease of the fibrinolysis activity. 2. In cardiac operations a more emphasized change in the clotting mechanism oceured than in the other operations. 3. The greatest deviation of the clotting mechanism was observed during the first postoperative week, which normalised during 3 weeks. It is concluded that the described changes of blood coagulation point during the first postoperative week toward an increased blood clotting tendency. With a hypcrcoagulability of the clotting mechanism a precondition is given for the onset of thromboembolic complications.Zusammen]assung, In der Einleitung wird die Annahme begriindet, dal3 Untersuchungen der Blutgerinnung im AnschluB an Thoraxeingriffe in besonderem FfaBe die Chance bieten, AnhMtspunkte fiir eine postoperative Thromboemboliege-f~hrdung zu gewinnen. Die Untersuehungen wurden bei insgesamt 50 Kranken vor-* Mit freundlieher Unterstiitzung der Deutschen Forschungsgemeinsch~ft.
Shotwounds in PeacetimeSummary. The Author publishes the shotwounds treated in the Department of Surgery of the University of Bonn since the war. In 42 fresh and I old shotwounds (boltshot) the chest was opened in 17 instances, the abdominal and the pelvic cavities were opened 6 times. In 6 cases multiple-cavity-injuries occured. 6 shotwounds of the extremities, 6 injuries of the chestwall and 2 patients with wounds in the neck region were treated. In 3 cases larger nervs and in 4 main arteries were damaged. In connection with the multiple-cavity-injuries 2 cardiac lesions were observed. The treatment of the fresh shotwounds was in each case surgical. 31 patients healed without complications. In 8 cases the woundhealing was delayed or combined with other complications. 3 patients died. Because of an old boltshot injury of the liver special therapy prooved unneccessary.The danger and the therapeutic problems of penetrating multiple or multiplecavity-injuries can be demonstrated readily with the example of shotwounds. The therapeutic task requires more than to exise the wound according to surgical standards. In all shotwounds of the trunc the possibility of major intrathoracic and intraabdominal lesions has to be considered. 5*
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.