Negative differential resistance (NDR) has been observed for the first time above room temperature in gallium nitride nanocrystals synthesized by a simple chemical route. Current-voltage characteristics have been used to investigate this effect through a metal-semiconductor-metal (M-S-M) configuration on SiO2. The NDR effect is reversible and reproducible through many cycles. The threshold voltage is approximately 7 V above room temperature.

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We herein report a nanoparticle‐directed therapeutic approach to breast cancer using Ag‐CuO hybrid nanoparticles. The nanoparticles were synthesized through redox‐mediated process involving reduction of silver ion on the surface of Cu2O nanostructures. Structural, microstructural and optical characterization were carried out and the hybrid nanoparticles were found to be phase pure with crystallite size between 100–200 nm and the absorption due to surface plasmon resonance from silver was observed around 460 nm. The binding affinities of the hybrid nanoparticles with the plasma protein BSA and calf thymus DNA were studied and the respective binding constants were found to be 5.1 × 104 and 1.12 × 105 M−1 showing appreciable binding affinity of the substrate. The cytotoxicity of the as‐synthesized hybrid nanoparticles induced in breast cancer cells was evaluated in vitro and the obtained results demonstrates the potential anti‐cancer activity of the Ag‐CuO hybrid nanoparticles against the MCF‐7 breast cancer cell line.

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