Three-dimensional encapsulation of cells within nanostructured silica gels or matrices enables applications as diverse as biosensors, microbial fuel cells, artificial organs, and vaccines; it also allows the study of individual cell behaviors. Recent progress has improved the performance and flexibility of cellular encapsulation, yet there remains a need for robust scalable processes. Here, we report a spray-drying process enabling the large-scale production of functional nano-biocomposites (NBCs) containing living cells within ordered 3D lipid-silica nanostructures. The spray-drying process is demonstrated to work with multiple cell types and results in dry powders exhibiting a unique combination of properties including highly ordered 3D nanostructure, extended lipid fluidity, tunable macromorphologies and aerodynamic diameters, and unexpectedly high physical strength. Nanoindentation of the encasing nanostructure revealed a Young's modulus and hardness of 13 and 1.4 GPa, respectively. We hypothesized this high strength would prevent cell growth and force bacteria into viable but not culturable (VBNC) states. In concordance with the VBNC state, cellular ATP levels remained elevated even over eight months. However, their ability to undergo resuscitation and enter growth phase greatly decreased with time in the VBNC state. A quantitative method of determining resuscitation frequencies was developed and showed that, after 36 weeks in a NBC-induced VBNC, less than 1 in 10,000 cells underwent resuscitation. The NBC platform production of large quantities of VBNC cells is of interest for research in bacterial persistence and screening of drugs targeting such cells. NBCs may also enable long-term preservation of living cells for applications in cell-based sensing and the packaging and delivery of live-cell vaccines.

Khwarezmian linguistic studies have progressed but slowly since their inception in 1927, when A. Z. V. Togan published his discovery of some Khwarezmian (hereafter Xw.) sentences in an Arabic fiqh book. W. B. Henning's first article appeared after nine years and a quarter of a century later H. W. Bailey could still refer to ‘the slowly emerging Chorasmian’. The latest bibliography cannot boast more than two dozen titles. It is our tragic loss that Henning, having studied all the available Xw. material in the course of four decades, should have left ready for publication only the first 260 entries (from '– to ' kiv) of the Khwarezmian dictionary on which he was working at his most untimely death. Of course, Togan's publication in 1951 of the facsimile of a manuscript of Zamakhshari's Arabic dictionary Muqaddimatu 'l-adab, almost completely glossed in Xw., made the greater part of the extant Xw. material generally available, but, not least because of the labour involved, few have cared to duplicate or anticipate Henning's work. Now suddenly, however, in the words of a colleague, ‘everyone has become a Khwarezmologist’, through the publication of a transliteration and translation of this same linguistic material by Johannes Benzing.

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This fourth article brings us to the end of a preliminary survey of the main chapter (six-sevenths by length of what survives) of Das chwaresmische Sprach-material einer Handschrift der ‘Muqaddimat al-adab’von Zamaxsari, as it is presented in the edition of Johannes Benzing. Notice is no longer taken of the underpointed spellings of words which have been met frequently before, of the type b'rwzd for p-, ǰrm for č-, etc., and in the first instance only the more debatable transliterations of the Xw. glosses are discussed. We take up the tale at Muq., 439, Benzing's p. 316.

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