Tri-o-thymotide forms molecular inclusion compounds with many substances such as alkanes and their derivatives including alkyl halides, alcohols, esters, ketones, ethers, and polymethylene dihalides. If the included molecule does not differ much from the " straight " chain type, the resulting compound belongs to one of two classes. A clathrate type, 2C,,H3,O6,M, is formed with included molecules, M, of greatest length less than 9.5 A. Longer molecules are enclosed in a different channel-type structure of composition C3,H3,06,xM where x , which need not be rational, diminishes with increasing length of the included molecule. Several ordered and disordered variations of the two structures have been found. Some of the channel structures give one-dimensional diffraction patterns, due to included molecules, superposed on the main single-crystal X-ray diffraction pattern. The unit-cell dimensions of the clathrate type increase slightly and in a regular manner to accommodate the larger included molecules. For the channel type the cell dimensions are more nearly constant but vary in a periodic way as the length of included molecules increases.Each of the 50 compounds studied is a new example of spontaneous optical resolution.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.