A CLX® (Cutter Laboratories, Berkeley, Calif.) bag system was evaluated for storage of single-donor
apheresis platelets collected with the Haemonetics V-50 blood processor. Concentrates (n = 21) containing 3.9-
5.2x10^11 platelets in 292 (±41.8) ml were stored in two 1 -liter bags for 7 days at 22 °C. pH was well maintained,
declining from an initial pH of 7.0 (±0.04) to 6.92 (±0.20) after 7 days. Platelet morphology, response to a
hypotonic stimulus and aggregation induced by paired agonists (epinephrine and ADP, or collagen) were also
well-preserved. Concentrates with a wide variation of platelet yields (2.0 ≥ 5.2x10^11, n = 43) also maintained pH
(6.96±0.26), morphology and aggregation when stored for 7 days. All platelet concentrates (n=64) were sterile at
collection. Single-donor apheresis platelets may be stored in this bag system for up to 7 days.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.