SummaryA total of 240 DBA I mice were given one intraperitoneal injection of P32. The experimental group was given a 0.2 percent aqueous solution of cystamine for a 60-day period as drinking water; controls received only ordinary water. The protective effect of cystamine per os against the radiotoxicity of P32 was statistically significant.The L. D. 50/30 days was estimated 4.5 μc/gm for the control group and 6.1 μc/gm for the cystamine group.The biological half-life of P32 in DBA I mice was estimated to be 8.1 days.A 9-percent retention out of the initial dose, corrected for physical decay, was found in DBA I mice after a 3-month period.
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