SummaryAlthough histamine release is recognised as a common event during anaesthesia and surgery, few clinicians judge the resultant cardiorespiratory disturbances serious enough to warrant prophylaxis with antihistamines. We have assessed the incidence and importance of histamine release in a randomised 2 × 2 factorial study. 240
ProblemstellungUnter Anaphylaxie versteht man eine akute systemische Reaktion mit Symptomen einer allergischen Sofortreaktion, die den ganzen Organismus erfassen kann und potenziell lebensbedrohlich ist [1-3].Die De nition der Anaphylaxie ist weltweit nicht einheitlich. Derzeit werden verschiedene Klassikationssysteme verwendet. Im deutschen Sprach-
Entwicklungsstufe
S2
AWMF-Leitlinien-Register-Nummer
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