Dental anomalies coincide with genetic disorders, and prenatal identification may contribute to a more accurate diagnosis. The aim of this study was to assess whether fetal Magnet Resonance Imaging (MRI) is suitable to visualize and investigate intrauterine dental development in the upper jaw, and to compare the quality of visibility of tooth buds between 1.5 Tesla (T) and 3T images. MR images of fetuses Gestational Week (GW) 26.71 ± 4.97 from 286 pregnant women with diagnoses unrelated to dental anomalies were assessed by three raters. We compared the visibility between groups and field strengths in five gestational age groups, using chi square and Fisher’s exact tests. All ten primary tooth buds were identifiable in 5.4% at GW 18–21, in 75.5% at GW 26–29, and in 90.6% at GW 34+. Before GW 30, more tooth buds were identifiable on 3T images than on 1.5T images. Statistical significance was only reached for identification of incisors (p = 0.047). Therefore, 1.5T and 3T images are viable to visualize tooth buds, particularly after GW 25, and their analysis may serve as diagnostic criterion. MRI tooth bud data might have an impact on various fields of research, such as the maldevelopment of teeth and their causes. Analyzing tooth buds as an additional diagnostic criterion is not time consuming, and could lead to an improvement of syndrome diagnosis.
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The role of prenatal diagnosis in placenta accreta spectrum (PAS) disorders is to reduce the risk of maternal complications by allowing a preplanned management. Although ultrasound (US) is the first diagnostic tool of choice, Magnetic Resonance Images (MRI) contributes in assessing the location, extension and depth of the invasion. Our objective is to describe the most characteristic features of PAS by MRI and correlate them with US, surgical and anatomopathological findings. Methods: We retrospectively reviewed prenatal MRI of patients with suspected diagnosis of PAS treated at our institution from 2015 to 2017. MRI were performed with standardised protocols to evaluate placenta. Localisation and extension of the abnormality was identified and correlated with US, macroscopic and histopathological findings. Results: During this period 41 patients with PAS were studied. All cases had heterogeneous placental showed as irregular venous lakes in US which by MRI corresponded to abnormal intraplacental blood vessels and thick dark bands on T2 weighted images (T2WI). These latter were correlated with fibrin deposits in the histopathologic evaluation. Conclusions: In our experience, abnormal intraplacental vascularisation together with thick hypointense bands on T2WI constitute the most frequent MRI findings to determine the presence, location and extension of PAS disorders. Therefore, MRI is currently considered a highly useful diagnostic tool for surgical planning of these patients.
Electronic poster abstracts differential diagnosis, dandy walker, Blake's pouch cyst, Vermian hypoplasia. BV angel was 66 • and we diagnosed Dandy walker. The patient decided to continue with the pregnancy and did not want to take amniocentesis after enough counselling. After that, BPD and ventricle were getting normal size, elevation cerebellar vermis and ventriculomegaly disappeared at 30w. MRI image at 31w revealed only hypoplasia cerebellar vermis and corpus callosum loss.In fetus, CNS was developing and after birth kept change. We have to know that we should become careful to diagnose and explanation of prognosis at 2nd trimester. Objectives: Aim of this study was to evaluate the reproducibility of intracranial anatomy assessment including measurements of the lateral ventricle, cisterna magna and transverse cerebellar diameter during the mid-trimester sonographic scan. Methods: Women undergoing mid-trimester scan (18th to 25th week) for fetal anatomy assessment were invited to participate in the study. Measurements of the lateral ventricle, cisterna magna, and transverse cerebellar diameter were obtained for reproducibility analysis'. Inter-observer and intraobserver reproducibility analysis' were made with correlation coefficients. Mean difference between different observers and in-between same observers were analysed with Bland-Altman plots. Results: A total of 162 women were included in the analysis. Correlation coefficient (CC) of cisterna magna measurements have shown weak to moderate interclass correlation (r=0.28, P=0.001) and strong intraclass correlation (r=0.81, P<0.0001). Measurements of lateral ventricle have shown moderate to strong interclass correlation (r=0.73, P<0.0001) and strong intraclass correlation (r=0.91, P<0.0001). Transverse cerebellar diameter measurements have shown the best interclass and intraclass correlation in-between studied parameters (r=0.88 and 0.91, respectively P<0.0001). Mean difference between different observers were -0.4mm (95% CI: -3.0 to 2.1mm), 0.7mm (95% CI: -1.0 to 2.5mm) and 0.53mm (95% CI: -2.5 to 3.6mm) for measurements of cerebellum, lateral ventricle and cisterna magna, respectively. When grouped according to BMI and presentation, there was no difference between groups regarding the prevalence of an absolute difference greater than 1mm between paired measurements by different observers. Conclusions: Measurements of TCD, LV, and CM during mid-trimester scan have good intra-observer reliability and good inter-observer reliability with the exception of CM measurements. Methods used for measuring these structures have shown good consistency between different BMI categories and different fetal presentations. EP03: IMPROVING THE PRENATAL DIAGNOSIS OF FETAL BRAIN AND CNS ANOMALIES EP03.02Impact of fetal magnetic resonance imaging of the brain in assessment of fetal CNS anomalies M.R. Louis Radio-Diagnosis, Cairo University, Giza, EgyptObjectives: To analyse the impact of MRI of the fetal brain and if it adds to the routine antenatal ultrasound study in the secon...
Oral communication abstractsstimulation. It is unlikely that melatonin exerts any effect on ovarian or uterine blood flow that might promote an improvement in IVF success. Paulo, Ribeirao Preto, São Paulo, Brazil; 3 Ludwin and Ludwin Gynecology, Krakow, Malopolska, Poland; 4 Reproductive Medicine, SEMEAR Fertilidade, Ribeirao Preto, Brazil Objectives: To evaluate an association between the diagnosis of septate uterus using ESHRE-ESGE and ASRM criteria with infertility and previous miscarriage. Methods: 261 women of reproductive age presented to assessment in single medical centre were consecutively evaluated to presence of uterus septate by an experienced observer using 3D-US in a prospective observational study. Septate uterus was recognised according to ESHRE-ESGE criteria (internal fundal indentation on coronal view > 50% uterine wall thickness; external cleft < 50% uterine wall thickness) and according to ASRM classification supplemented by additional morphometric criteria (internal fundal indentation ≥ 1.5cm, external cleft < 1cm). Proportions were compared with Fisher's exact test. Results: There were 44/261 (17%) and 16/261 (6%) septate uteri according to ESHRE-ESGE and ASRM classification (p<0.001). There were no significant differences in the proportion of septate uteri in women with and without infertility by both systems (ASRM: 6/98=6% vs. 10/163=6%, P = 1.00; ESHRE-ESGE: 16/98=16% vs. 28/163=17%, P = 1.00). Septate uterus by ASRM was significantly more frequent in women with previous miscarriage (6/45=13% vs. 28/163= 5%; P = 0.04); but there was no significant differences proportion of septate uteri by ESHRE-ESGE in women with and without previous miscarriage (10/45, 22% vs. 34/216, 16%; P = 0.28). Conclusions: Diagnosis of septate uterus by ESHRE-ESGE and ASRM criteria is not higher in women with infertility and the diagnosis of septate uterus only by ASRM criteria is associated with previous miscarriage. A significantly higher proportion of uterus are classified as being septate using ESHRE-ESGE criteria; and this diagnosis seems to have no clinical relevance. Objectives: Uterine transplantation (UTx) has been proposed as a treatment option for women diagnosed with absolute uterine factor infertility (AUFI). Imaging of the pelvis is an important step in preparing a patient for a potential transplant. The study aims were to describe the ovaries with regards to fertility treatment and assess blood flow within the pelvic vessels with regards to vascular anastomosis during UTx. OC04.04 Septate uterus by ESHRE-ESGE and ASRM classification: association with infertility and previous miscarriageMethods: All women were seen in a specialist clinic (Queen Charlotte's Hospital, London). They had undergone a careful and detailed selection process and represented the first UK cohort of patients awaiting UTx. They underwent 2D/3D transvaginal and transabdominal ultrasonography using a Samsung WS80 Elite system (Samsung Medison Co. Ltd., Seoul, Republic of Korea). Doppler studies were applied to assess pe...
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