OC05.01: Malformation or acquired lesion?

Abstract

Oral communication abstractsstimulation. It is unlikely that melatonin exerts any effect on ovarian or uterine blood flow that might promote an improvement in IVF success. Paulo, Ribeirao Preto, São Paulo, Brazil; 3 Ludwin and Ludwin Gynecology, Krakow, Malopolska, Poland; 4 Reproductive Medicine, SEMEAR Fertilidade, Ribeirao Preto, Brazil Objectives: To evaluate an association between the diagnosis of septate uterus using ESHRE-ESGE and ASRM criteria with infertility and previous miscarriage. Methods: 261 women of reproductive age presented to assessment in single medical centre were consecutively evaluated to presence of uterus septate by an experienced observer using 3D-US in a prospective observational study. Septate uterus was recognised according to ESHRE-ESGE criteria (internal fundal indentation on coronal view > 50% uterine wall thickness; external cleft < 50% uterine wall thickness) and according to ASRM classification supplemented by additional morphometric criteria (internal fundal indentation ≥ 1.5cm, external cleft < 1cm). Proportions were compared with Fisher's exact test. Results: There were 44/261 (17%) and 16/261 (6%) septate uteri according to ESHRE-ESGE and ASRM classification (p<0.001). There were no significant differences in the proportion of septate uteri in women with and without infertility by both systems (ASRM: 6/98=6% vs. 10/163=6%, P = 1.00; ESHRE-ESGE: 16/98=16% vs. 28/163=17%, P = 1.00). Septate uterus by ASRM was significantly more frequent in women with previous miscarriage (6/45=13% vs. 28/163= 5%; P = 0.04); but there was no significant differences proportion of septate uteri by ESHRE-ESGE in women with and without previous miscarriage (10/45, 22% vs. 34/216, 16%; P = 0.28). Conclusions: Diagnosis of septate uterus by ESHRE-ESGE and ASRM criteria is not higher in women with infertility and the diagnosis of septate uterus only by ASRM criteria is associated with previous miscarriage. A significantly higher proportion of uterus are classified as being septate using ESHRE-ESGE criteria; and this diagnosis seems to have no clinical relevance. Objectives: Uterine transplantation (UTx) has been proposed as a treatment option for women diagnosed with absolute uterine factor infertility (AUFI). Imaging of the pelvis is an important step in preparing a patient for a potential transplant. The study aims were to describe the ovaries with regards to fertility treatment and assess blood flow within the pelvic vessels with regards to vascular anastomosis during UTx. OC04.04 Septate uterus by ESHRE-ESGE and ASRM classification: association with infertility and previous miscarriageMethods: All women were seen in a specialist clinic (Queen Charlotte's Hospital, London). They had undergone a careful and detailed selection process and represented the first UK cohort of patients awaiting UTx. They underwent 2D/3D transvaginal and transabdominal ultrasonography using a Samsung WS80 Elite system (Samsung Medison Co. Ltd., Seoul, Republic of Korea). Doppler studies were applied to assess pe...