Review question / Objective: The combination of high-intensity focused ultrasound (HIFU), and uterine artery embolization (UAE) with uterine curettage has been proposed as a therapy strategy for cesarean scar pregnancy (CSP), which can provide a high success rate while reducing blood loss, adverse events, hospital time and cost. Therefore, we performed this meta-analysis to assess the effects of this combination therapy on the efficacy, safety, and pregnancy outcomes in patients with CSP. Eligibility criteria: (1) Study design: Cohort, case-control, or randomized controlled trials that compare the efficacy, safety, and recurrence of UAE combined with curettage and HIFU combined with uterine scraping in the treatment of cesarean section scar pregnancy. (2) Outcome: Success rate, blood loss, time of β-hCG normalization, adverse events, length of stay, hospital costs, menstrual recovery, re-pregnancy status, and pain score.
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