Endereço para correspondênciaRev Psiquiatr RS. 2008;30(1 Supl). RESUMOO presente estudo inclui ensaios clínicos randomizados, controlados ou não, a respeito do tratamento farmacológico de comprar compulsivo, publicados em inglês ou em português nas bases MEDLINE, PsycINFO, Biological Abstracts e Cochrane Central Register of Controlled Trials. De todos os seis artigos selecionados, apenas dois eram estudos duplo-cegos controlados com placebo desde o princípio, e um terceiro era composto de uma fase inicial aberta seguida de uma segunda fase randomizada e placebo-controlada. É importante destacar que, em todos os estudos, pacientes com transtorno afetivo bipolar foram excluídos. Todos os ensaios envolveram amostras pequenas (variaram de 10 a 42 pacientes). De maneira geral, as evidências atualmente disponíveis a respeito do tratamento farmacológico de comprar compulsivo são pobres, em virtude da escassez de mais estudos metodologicamente bem conduzidos.Descritores: Transtorno obsessivo-compulsivo, comportamento compulsivo, transtornos do controle de impulsos. ABSTRACTThis study included randomized and non-randomized controlled trials on pharmacological treatment of compulsive buying published in English or Portuguese. Databases evaluated were MEDLINE, PsycINFO, Biological Abstracts and Cochrane Central Register of Controlled Trials. Of all six selected articles, only two were placebo-controlled randomized trials, and one had a first open-label phase followed by a second placebo-controlled phase. It is important to stress that all studies excluded bipolar patients. All the studies reviewed included small samples (from 10 to 42 patients). Current available evidence regarding pharmacological treatment of compulsive buying is poor due to the lack of studies using more rigorous methodology.
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